ReviewMolecular metabolism2016
Microscopy tools for the investigation of intracellular lipid storage and dynamics.
Review in Molecular metabolism, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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Who cites it
44 citing papers in PubMed, 113 citations in OpenAlex.
- An optimized method to visualize lipid droplets in mouse brain tissue.Cell reports methods · 2026Article
- Lipid droplet dynamics in metabolic regulation.RSC chemical biology · 2026Review
- Mechanism-based new approach methodologies for in vitro detection of chemical-induced liver steatosis.Archives of toxicology · 2026Review
- Review
- PEDF and Its Role in Metabolic Disease, Angiogenesis, Cardiovascular Disease, and Diabetes.Biomedicines · 2025Review
- Label-free high-throughput live-cell sorting of genome-wide random mutagenesis libraries for metabolic traits by Raman flow cytometry.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Synthetic Lipid Biology.Chemical reviews · 2025Review
- Endosomal trafficking participates in lipid droplet catabolism to maintain lipid homeostasis.Nature communications · 2025Article
- Unilocular adipocyte and lipid tracer for immunofluorescent images.Scientific reports · 2025Article
- Activation of lysosomal Ca2+ channels mitigates mitochondrial damage and oxidative stress.The Journal of cell biology · 2025Article
- Aggregation-Induced Emission Photosensitizer Boosting Algal Growth and Lipid Accumulation.Small (Weinheim an der Bergstrasse, Germany) · 2024Article
- A fluorescent perilipin 2 knock-in mouse model reveals a high abundance of lipid droplets in the developing and adult brain.Nature communications · 2024Article
- STAT3 drives the expression of ACSL4 in acute kidney injury.iScience · 2024Article
- Differential lipid analysis of oxaliplatin-sensitive and resistant HCT116 cells reveals different levels of drug-induced lipid droplet formation.Analytical and bioanalytical chemistry · 2024Article
- What's past is prologue: FRAP keeps delivering 50 years later.Biophysical journal · 2023Review
- Lipid metabolism transcriptomics of murine microglia in Alzheimer's disease and neuroinflammation.Scientific reports · 2023Article
- Investigating ionizing radiation-induced changes in breast cancer cells using stimulated Raman scattering microscopy.Journal of biomedical optics · 2023Article
- Methodological advancements in organ-specific ectopic lipid quantitative characterization: Effects of high fat diet on muscle and liver intracellular lipids.Molecular metabolism · 2023Article
- Indane-1,3-Dione: From Synthetic Strategies to Applications.Molecules (Basel, Switzerland) · 2022Review
- Different Seasonal Collections ofNutrients · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExcess storage of lipids in ectopic tissues, such as skeletal muscle, liver, and heart, seems to associate closely with metabolic abnormalities and cardiac disease. Intracellular lipid storage occurs in lipid droplets, which have gained attention as active organelles in cellular metabolism. Recent developments in high-resolution microscopy and microscopic spectroscopy have opened up new avenues to examine the physiology and biochemistry of intracellular lipids. SCOPE OF REVIEW: The aim of this review is to give an overview of recent technical advances in microscopy, and its application for the visualization, identification, and quantification of intracellular lipids, with special focus to lipid droplets. In addition, we attempt to summarize the probes currently available for the visualization of lipids. MAJOR
conclusionsThe continuous development of lipid probes in combination with the rapid development of microscopic techniques can provide new insights in the role and dynamics of intracellular lipids. Moreover, in situ identification of intracellular lipids is now possible and promises to add a new dimensionality to analysis of lipid biochemistry, and its relation to (patho)physiology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.