ArticleBiomedical optics express2016
Quantitative optical coherence elastography based on fiber-optic probe for in situ measurement of tissue mechanical properties.
Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Phantoms for use in optical coherence elastography.Journal of biomedical optics · 2026Review
- Article
- Analysis of friction in quantitative micro-elastography.Biomedical optics express · 2023Article
- Label-free full-field Doppler phase microscopy based on optical computation.Biomedical optics express · 2023Article
- Analysis of strain estimation methods in phase-sensitive compression optical coherence elastography.Biomedical optics express · 2022Article
- Manually scanned single fiber optical coherence tomography for skin cancer characterization.Scientific reports · 2021Article
- Quantitative characterization of human breast tissue based on deep learning segmentation of 3D optical coherence tomography images.Biomedical optics express · 2021Article
- Optical coherence viscometry.Applied physics letters · 2021Article
- Fluid surface tension evaluation using capillary wave measurement with optical coherence tomography.AIP advances · 2020Article
- Clinical Corneal Optical Coherence Elastography Measurement Precision: Effect of Heartbeat and Respiration.Translational vision science & technology · 2020Article
- Optically computed optical coherence tomography for volumetric imaging.Optics letters · 2020Article
- Optical coherence tomography for evaluating capillary waves in blood and plasma.Biomedical optics express · 2020Article
- Spatial coordinate corrected motion tracking for optical coherence elastography.Proceedings of SPIE--the International Society for Optical Engineering · 2020Article
- Spatial coordinate corrected motion tracking for optical coherence elastography.Biomedical optics express · 2019Article
- Scanning optical coherence tomography probe for in vivo imaging and displacement measurements in the cochlea.Biomedical optics express · 2019Article
- Adaptive Doppler analysis for robust handheld optical coherence elastography.Proceedings of SPIE--the International Society for Optical Engineering · 2019Article
- OCE quantification of Poisson's ratio through 2D speckle tracking.Proceedings of SPIE--the International Society for Optical Engineering · 2019Article
- Quantitative Optical Coherence Elastography for Robust Stiffness Assessment.Applied sciences (Basel, Switzerland) · 2018Article
- Temporally and spatially adaptive Doppler analysis for robust handheld optical coherence elastography.Biomedical optics express · 2018Article
- Assessment and removal of additive noise in a complex optical coherence tomography signal based on Doppler variation analysis.Applied optics · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We developed a miniature quantitative optical coherence elastography (qOCE) instrument with an integrated Fabry-Perot force sensor, for in situ elasticity measurement of biological tissue. The technique has great potential for biomechanics modeling and clinical diagnosis. We designed the fiber-optic qOCE probe that was used to exert a compressive force to deform tissue at the tip of the probe. Using the space-division multiplexed optical coherence tomography (OCT) signal detected by a spectral domain OCT engine, we were able to quantify the probe deformation that was proportional to the force applied, and to quantify the tissue deformation corresponding to the external stimulus. Simultaneous measurement of force and displacement allowed us to extract Young's modulus of biological tissue. We experimentally calibrated our qOCE instrument, and validated its effectiveness on tissue mimicking phantoms and biological tissues.
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