ArticleBiomedical optics express2016
Lock-in-photon-counting-based highly-sensitive and large-dynamic imaging system for continuous-wave diffuse optical tomography.
Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed.
- Reflective optical imaging for scattering medium using chaotic laser.Journal of biomedical optics · 2024Article
- CGAN-rIRN: a data-augmented deep learning approach to accurate classification of mental tasks for a fNIRS-based brain-computer interface.Biomedical optics express · 2023Article
- Deep-learning informed Kalman filtering for priori-free and real-time hemodynamics extraction in functional near-infrared spectroscopy.Biomedical optics express · 2022Article
- An LBiomedical engineering online · 2017Article
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7 authors.
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Abstract
We implemented a novel lock-in photon-counting detection architecture that combines the ultra-high sensitivity of the photon-counting detection and the measurement parallelism of the lock-in technique. Based on this technique, a dual-wavelength simultaneous measurement continuous wave diffuse optical tomography system was developed with a configuration of 16 sources and 16 detectors that works in a tandem serial-to-parallel fashion. Methodology validation and performance assessment of the system were conducted using phantom experiments that demonstrate excellent measurement linearity, moderate-term system stability, robustness to noise and negligible inter-wavelength crosstalk. 2-D imaging experiments further validate high sensitivity of the lock-in photon-counting methodology as well as high reliability of the proposed system. The advanced detection principle can be adapted to achieving a fully parallelized instrumentation for the extended applications.
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