Evidence map›Paper›PMID 26977353›Full record

ArticleBiomedical optics express2016

Light controlled drug delivery containers based on spiropyran doped liquid crystal micro spheres.

Gia Petriashvili, Lali Devadze, Tsisana Zurabishvili, Nino Sepashvili, Ketevan Chubinidze

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gia PetriashviliInstitute of Cybernetics of the Georgian Technical University, Tbilisi, 0175, Georgia.
Lali DevadzeInstitute of Cybernetics of the Georgian Technical University, Tbilisi, 0175, Georgia.
Tsisana ZurabishviliInstitute of Cybernetics of the Georgian Technical University, Tbilisi, 0175, Georgia.
Nino SepashviliInstitute of Cybernetics of the Georgian Technical University, Tbilisi, 0175, Georgia.
Ketevan ChubinidzeIvane Javakhishvili Tbilisi State University, 1 Ilia Chavchavadze Ave, Tbilisi 0179, Georgia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have developed a novel, light activated drug delivery containers, based on spiropyran doped liquid crystal micro spheres. Upon exposure to UV/violet light, the spiropyran molecules entrapped inside the nematic liquid crystal micro spheres, interconvert from the hydrophobic, oil soluble form, to the hydrophilic, water soluble merocyanine one, which stimulates the translocation of the merocyanine molecules across the nematic liquid crystal-water barrier and results their homogeneous distribution throughout in an aqueous environment. Light controllable switching property and extremely high solubility of spiropyran in the nematic liquid crystal, promise to elaborate a novel and reliable vehicles for the drug delivery systems.

Indexed as

(160.0160) Materials(160.3710) Liquid crystals(160.5335) Photosensitive materials

Identifiers

PMID26977353
PMCPMC4771462

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.