Evidence map›Paper›PMID 26977336›Full record

ArticleBiomedical optics express2016

Investigation of middle ear anatomy and function with combined video otoscopy-phase sensitive OCT.

Jesung Park, Jeffrey T Cheng, Daniel Ferguson, Gopi Maguluri, Ernest W Chang, Caitlin Clancy, Daniel J Lee, Nicusor Iftimia

Abstract read
In one paragraph

Article in Biomedical optics express, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Journal of biomedical optics · 2023
    Article
  5. Mammalian middle ear mechanics: A review.Frontiers in bioengineering and biotechnology · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jesung ParkPhysical Sciences Inc., Andover, MA 01810, USA.
Jeffrey T ChengEaton-Peabody Laboratories, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA.
Daniel FergusonPhysical Sciences Inc., Andover, MA 01810, USA.
Gopi MaguluriPhysical Sciences Inc., Andover, MA 01810, USA.
Ernest W ChangPhysical Sciences Inc., Andover, MA 01810, USA.
Caitlin ClancyPhysical Sciences Inc., Andover, MA 01810, USA.
Daniel J LeeEaton-Peabody Laboratories, Massachusetts Eye and Ear Infirmary, Boston, MA 02114, USA.
Nicusor IftimiaPhysical Sciences Inc., Andover, MA 01810, USA.

Funding

Functional otoscopy for non-invasive diagnosis of middle ear pathologiesR43DC013923 · NIDCD · PHYSICAL SCIENCES, INC · PI IFTIMIA, NICUSOR · 2014 to 2014
$198k
NIDCD NIH HHS R43 DC013923
6 · The paper itself

Abstract

We report the development of a novel otoscopy probe for assessing middle ear anatomy and function. Video imaging and phase-sensitive optical coherence tomography are combined within the same optical path. A sound stimuli channel is incorporated as well to study middle ear function. Thus, besides visualizing the morphology of the middle ear, the vibration amplitude and frequency of the eardrum and ossicles are retrieved as well. Preliminary testing on cadaveric human temporal bone models has demonstrated the capability of this instrument for retrieving middle ear anatomy with micron scale resolution, as well as the vibration of the tympanic membrane and ossicles with sub-nm resolution.

Indexed as

(110.4500) Optical coherence tomography(120.5050) Phase measurement(120.7280) Vibration analysis(170.4940) Otolaryngology

Identifiers

PMID26977336
PMCPMC4771445

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.