Evidence map›Paper›PMID 26977280›Full record

ReviewTherapeutic advances in chronic disease2016

New perspectives on management of idiopathic pulmonary fibrosis.

Silvia Puglisi, Sebastiano Emanuele Torrisi, Virginia Vindigni, Riccardo Giuliano, Stefano Palmucci, Massimiliano Mulè, Carlo Vancheri

Open access · bronzeAbstract readReview
In one paragraph

Review in Therapeutic advances in chronic disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 37 citations in OpenAlex.

  1. Vascular Contribution to Lung Repair and Fibrosis.American journal of respiratory cell and molecular biology · 2023
    Review
  2. Article
  3. Prognostic Significance of Red Cell Distribution Width in Idiopathic Pulmonary Fibrosis and Combined Pulmonary Fibrosis Emphysema.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2021
    Article
  4. Review
  5. Review
  6. Article
  7. Gastric Acid and Pepsin Work Together in Simulated Gastric Acid Inhalation Leading to Pulmonary Fibrosis in Rats.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  8. Article
  9. Article
  10. Idiopathic pulmonary fibrosis and GERD: links and risks.Therapeutics and clinical risk management · 2019
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Silvia PuglisiRegional Centre for Interstitial and Rare Lung Diseases, Department of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78 Catania, 95123, Italy silviapuglisi@fastwebnet.it.
Sebastiano Emanuele TorrisiRegional Centre for Interstitial and Rare Lung Diseases, Department of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78 Catania, 95123, Italy torrisiseby@hotmail.it.
Virginia VindigniRegional Centre for Interstitial and Rare Lung Diseases, Department of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78 Catania, 95123, Italy v-vindigni@hotmail.it.
Riccardo GiulianoRegional Centre for Interstitial and Rare Lung Diseases, Department of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78 Catania, 95123, Italy dottor.giuliano@gmail.com.
Stefano PalmucciRadiodiagnostic and Radiotherapy Unit-University Hospital "Policlinico-Vittorio Emanuele" Via Santa Sofia 78, Catania 95123-Italy spalmucci@sirm.org.
Massimiliano MulèUniversity of Catania - Division of Cardiology Ferrarotto Hospital, Catania, Italy medimaxim@gmail.com.
Carlo VancheriRegional Centre for Interstitial and Rare Lung Diseases, Department of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78 Catania, 95123, Italy.
University of Catania · ITAzienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive parenchymal lung disease characterized by a median survival of 3-5 years following diagnosis. The diagnosis is based on clinical, radiological and histopathological evaluation. Therefore, a multidisciplinary team is needed to reach the correct diagnosis. For a long time, supportive care and lung transplantation in selected cases, have been considered the only possible treatments for IPF. In the last decade many studies have investigated IPF pathogenesis, leading to an improved knowledge of the mechanisms underlying the disease and to the approval of two new drugs for IPF treatment (pirfenidone and nintedanib). The therapeutic approach of IPF cannot be limited to the administration of antifibrotic drugs, but it is necessary for improving the quality of life of patients and for facilitating, as far as possible, the performance of normal daily activities and relationships. IPF patients are also afflicted by disease-related complications such as gastroesophageal reflux, pulmonary hypertension, acute exacerbations and an increased risk of developing lung cancer. The clinician who treats IPF patients, should also treat these possible complications to slow disease progression, thus maintaining the possibility of a pulmonary transplantation.

Indexed as

exacerbationmanagementnintedanibpirfenidonepulmonary fibrosis

Identifiers

PMID26977280
PMCPMC4772343
OpenAlexW2302754197

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.