Evidence map›Paper›PMID 26977236›Full record

ArticleThe Pan African medical journal2015

Electroencephalography as a tool for evidence-based diagnosis and improved outcomes in children with epilepsy in a resource-poor setting.

Ike Oluwa Abiola Lagunju, Alexander Opebiyi Oyinlade, Omolola Mojisola Atalabi, Godwin Ogbole, Olushola Tedimola, Abimbola Famosaya, Adesola Ogunniyi, Ayotunde Oluremi Ogunseyinde, Ann Ragin

Open access · goldAbstract readComparative Study
In one paragraph

Article in The Pan African medical journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ike Oluwa Abiola LagunjuDepartment of Paediatrics, College of Medicine, University of Ibadan/University College Hospital, Ibadan, Nigeria.
Alexander Opebiyi OyinladeDepartment of Paediatrics, College of Medicine, University of Ibadan/University College Hospital, Ibadan, Nigeria.
Omolola Mojisola AtalabiDepartment of Radiology, College of Medicine, University of Ibadan/University College Hospital, Ibadan, Nigeria.
Godwin OgboleDepartment of Radiology, College of Medicine, University of Ibadan/University College Hospital, Ibadan, Nigeria.
Olushola TedimolaDepartment of Paediatrics, College of Medicine, University of Ibadan/University College Hospital, Ibadan, Nigeria.
Abimbola FamosayaDepartment of Paediatrics, College of Medicine, University of Ibadan/University College Hospital, Ibadan, Nigeria.
Adesola OgunniyiDepartment of Medicine, College of Medicine, University of Ibadan/University College Hospital, Ibadan.
Ayotunde Oluremi OgunseyindeDepartment of Radiology, College of Medicine, University of Ibadan/University College Hospital, Ibadan, Nigeria.
Ann RaginDepartment of Radiology, Northwestern University, Chicago, Illinois, USA.
University of Ibadan · NGUniversity College Hospital, Ibadan · NGNorthwestern University · US

Funding

Improving neurologic outcome measurement for interventional research in IbadanR25NS080949 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI EPSTEIN, LEON G, OGUNNIYI, ADESOLA · 2012 to 2014
$811k
NINDS NIH HHS 1R25NS080949NINDS NIH HHS R25 NS080949
6 · The paper itself

Abstract

introductionElectroencephalography (EEG) remains the most important investigative modality in the diagnostic evaluation of individuals with epilepsy. Children living with epilepsy in the developing world are faced with challenges of lack of access to appropriate diagnostic evaluation and a high risk of misdiagnosis and inappropriate therapy. We appraised EEG studies in a cohort of Nigerian children with epilepsy seen in a tertiary center in order to evaluate access to and the impact of EEG in the diagnostic evaluation of the cases.

methodsInter-ictal EEG was requested in all cases of pediatric epilepsy seen at the pediatric neurology clinic of the University College Hospital, Ibadan, Nigeria over a period of 18 months. Clinical diagnosis without EEG evaluation was compared with the final diagnosis post- EEG evaluation.

resultsA total of 329 EEGs were recorded in 329 children, aged 3 months to 16 years, median 61.0 months. Clinical evaluation pre-EEG classified 69.3% of the epilepsies as generalized. The a posteriori EEG evaluations showed a considerably higher proportion of localization-related epilepsies (33.6%). The final evaluation post EEG showed a 21% reduction in the proportion of cases labeled as generalized epilepsy and a 55% increase in cases of localization-related epilepsy(p<0.001).

conclusionHere we show that there is a high risk of misdiagnosis and therefore the use of inappropriate therapies in children with epilepsy in the absence of EEG evaluation. The implications of our findings in the resource-poor country scenario are key for reducing the burden of care and cost of epilepsy treatment on both the caregivers and the already overloaded tertiary care services.

Indexed as

ElectroencephalographyAdolescentChildChild, PreschoolEpilepsyEvidence-Based MedicineFemaleHealth ResourcesHumansInfantMalePovertychildhooddiagnosisEEGElectroencephalographyepilepsyoutcome and resource-poor countries

Identifiers

PMID26977236
PMCPMC4769815
OpenAlexW2182739974

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.