Evidence map›Paper›PMID 26977162›Full record

ArticleHepatitis monthly2015

Risk Factors for Portal Vein Thrombosis in Patients With Cirrhosis Awaiting Liver Transplantation in Shiraz, Iran.

Kamran Bagheri Lankarani, Katayon Homayon, Dorna Motevalli, Seyed Taghi Heidari, Seyed Moayed Alavian, Seyed Ali Malek-Hosseini

Open access · hybridAbstract read
In one paragraph

Article in Hepatitis monthly, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Portal Vein Thrombosis in Cirrhosis.Journal of clinical and experimental hepatology
    Review
  8. No Association of Homocysteine, Anticardiolipin Antibody, and Anti-β2 Glycoprotein I Antibody With Portal Venous System Thrombosis in Liver Cirrhosis.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kamran Bagheri LankaraniHealth Policy Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Katayon HomayonGastroenterology and Hepatology Rearch Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Dorna MotevalliHealth Policy Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Seyed Taghi HeidariHealth Policy Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Seyed Moayed AlavianResearch Center for Gastroenterology and Liver Diseases, Baghiatallah University of Medical Sciences, Tehran, IR Iran; Tehran Hepatitis Center , Tehran, IR Iran.
Seyed Ali Malek-HosseiniTransplant Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran.
Shiraz University of Medical Sciences · IRMiddle East Liver Disease Center · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPortal vein thrombosis is a fairly common and potentially life-threatening complication in patients with liver cirrhosis. The risk factors for portal vein thrombosis in these patients are still not fully understood.

objectivesThis study aimed to investigate the associations between various risk factors in cirrhotic patients and the development of portal vein thrombosis. PATIENTS AND

methodsIn this case-control study performed at the Shiraz organ transplantation center, Iran, we studied 219 patients (> 18 years old) with liver cirrhosis, who were awaiting liver transplants in our unit, from November 2010 to May 2011. The patients were evaluated by history, physical examination, and laboratory tests, including factor V Leiden, prothrombin gene mutation, Janus Kinase 2 (JAK2) mutation, and serum levels of protein C, protein S, antithrombin III, homocysteine, factor VIII, and anticardiolipin antibodies.

resultsThere was no statistically significant difference in the assessed hypercoagulable states between patients with or without portal vein thrombosis. A history of previous variceal bleeding with subsequent endoscopic treatment in patients with portal vein thrombosis was significantly higher than in those without it (P = 0.013, OR: 2.526, 95% CI: 1.200 - 5.317).

conclusionsIn our population of cirrhotic patients, treatment of variceal bleeding predisposed the patients to portal vein thrombosis, but hypercoagulable disorders by themselves were not associated with portal vein thrombosis.

Indexed as

Endoscopic TreatmentEsophageal VaricesIranLiver CirrhosisLiver TransplantationPortal Vein ThrombosisRisk Factors

Identifiers

PMID26977162
PMCPMC4779252
OpenAlexW2276895859

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.