Evidence map›Paper›PMID 26977153›Full record

ReviewInternational journal of otolaryngology2016

Sensorineural Tinnitus: Its Pathology and Probable Therapies.

Aage R Møller

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in International journal of otolaryngology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06821893 (Vagus Auricular Stimulation for Tinnitus), which is not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06821893 nacompletednot on this mapstarted 2025, after this paper: background citation

Vagus Auricular Stimulation for Tinnitus

TypeinterventionalSponsorWashington University School of MedicineRan2025 to 2025Enrolled40ConditionsTinnitusArmsVibrational stimulation, Sham
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. The role of GABAFrontiers in endocrinology · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Analysis of Factors Influencing the Efficiency of Acupuncture in Tinnitus Patients.Evidence-based complementary and alternative medicine : eCAM · 2019
    Article
  12. Article
  13. Article
  14. Article
  15. Somatosensory tinnitus: Current evidence and future perspectives.The Journal of international medical research · 2017
    Review
  16. Improving the Reliability of Tinnitus Screening in Laboratory Animals.Journal of the Association for Research in Otolaryngology : JARO · 2017
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Aage R MøllerThe University of Texas at Dallas, School of Behavioral and Brain Sciences, 800 W Campbell Road, Richardson, TX 75080, USA.
The University of Texas at Dallas · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tinnitus is not a single disease but a group of different diseases with different pathologies and therefore different treatments. Regarding tinnitus as a single disease is hampering progress in understanding of the pathophysiology of tinnitus and perhaps, more importantly, it is a serious obstacle in development of effective treatments for tinnitus. Subjective tinnitus is a phantom sound that takes many different forms and has similarities with chronic neuropathic pain. The pathology may be in the cochlea, in the auditory nerve, or, most commonly, in the brain. Like chronic neuropathic pain tinnitus is not life threatening but influences many normal functions such as sleep and the ability to concentrate on work. Some forms of chronic tinnitus have two components, a (phantom) sound and a component that may best be described as suffering or distress. The pathology of these two components may be different and the treatment that is most effective may be different for these two components. The most common form of treatment of tinnitus is pharmacological agents and behavioral treatment combined with sound therapy. Less common treatments are hypnosis and acupuncture. Various forms of neuromodulation are becoming in use in an attempt to reverse maladaptive plastic changes in the brain.

Identifiers

PMID26977153
PMCPMC4761664
OpenAlexW2253492200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.