Evidence map›Paper›PMID 26977101›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2016

Precision medicine: opportunities, possibilities, and challenges for patients and providers.

Samantha A Adams, Carolyn Petersen

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Precision oncology: transforming cancer care through personalized medicine.Medical oncology (Northwood, London, England) · 2025
    Review
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  14. The Impact of Communicating Uncertainty on Public Responses to Precision Medicine Research.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Samantha A AdamsTilburg Institute of Law, Technology and Society (TILT), Tilburg University, PO Box 90153, 5000 LE Tilburg, The Netherlands petersen.carolyn@mayo.edu.
Carolyn PetersenGlobal Business Solutions - BB 7, Mayo Clinic, 200 First St. SW, Rochester, MN 55905, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precision medicine approaches disease treatment and prevention by taking patients' individual variability in genes, environment, and lifestyle into account. Although the ideas underlying precision medicine are not new, opportunities for its more widespread use in practice have been enhanced by the development of large-scale databases, new methods for categorizing and representing patients, and computational tools for analyzing large datasets. New research methods may create uncertainty for both healthcare professionals and patients. In such situations, frameworks that address ethical, legal, and social challenges can be instrumental for facilitating trust between patients and providers, but must protect patients while not stifling progress or overburdening healthcare professionals. In this perspective, we outline several ethical, legal, and social issues related to the Precision Medicine Initiative's proposed changes to current institutions, values, and frameworks. This piece is not an exhaustive overview, but is intended to highlight areas meriting further study and action, so that precision medicine's goal of facilitating systematic learning and research at the point of care does not overshadow healthcare's goal of providing care to patients.

Indexed as

Patient ParticipationPrecision MedicineConfidentialityHealth PersonnelHumansInformed ConsentELSIequityinformed consentpatient engagementPrecision Medicineprivacy and data protection

Identifiers

PMID26977101
PMCPMC9396673

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.