ArticleProceedings of the National Academy of Sciences of the United States of America2016
Small genome of the fungus Escovopsis weberi, a specialized disease agent of ant agriculture.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed, 99 citations in OpenAlex.
- Evidence for Cryptic Sex in Escovopsis, a Mycoparasite in the Fungus-Growing Ant Symbiosis.Genome biology and evolution · 2026Article
- What makes a mycoparasite? Candidate effectors from fungi that parasitize other fungi exhibit structural homology to those of fungal plant pathogens.Fungal biology and biotechnology · 2026Article
- Towards a Novel Biocontrol Strategy: High Performance of Optimised Cell Wall-Degrading Enzymes Secreted by Escovopsis primorosea LBM 277.Environmental microbiology reports · 2026Article
- Plant recognition by Trichoderma Harzianum elicits upregulation of a novel secondary metabolite cluster required for colonization.Scientific reports · 2026Article
- Deciphering taxon-specific metabolic shifts during pathogenic fungal infection in leaf-cutter ant fungal gardens.ISME communications · 2026Article
- Identification and Classification of Fungal GPCR Gene Families.Journal of fungi (Basel, Switzerland) · 2025Article
- Digging into the evolutionary history of the fungus-growing-ant symbiont, Escovopsis (Hypocreaceae).Communications biology · 2025Article
- Massive Gene Loss in the Fungus Sporothrix epigloea Accompanied a Shift to Life in a Glucuronoxylomannan-based Gel Matrix.Genome biology and evolution · 2025Article
- From the inside out: Were the cuticularPNAS nexus · 2024Article
- Comparative genomic analysis of thermophilic fungi reveals convergent evolutionary adaptations and gene losses.Communications biology · 2024Article
- Article
- The fungusFrontiers in fungal biology · 2024Review
- Taxonomy and systematics of the fungus-growing ant associateStudies in mycology · 2023Article
- Article
- The Sordariomycetes: an expanding resource with Big Data for mining in evolutionary genomics and transcriptomics.Frontiers in fungal biology · 2023Review
- Optimization of the "Ecology and evolution · 2023Article
- Genomic diversification of the specialized parasite of the fungus-growing ant symbiosis.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Masters of the manipulator: two new hypocrealean genera,Persoonia · 2022Article
- The pangenome of the wheat pathogen Pyrenophora tritici-repentis reveals novel transposons associated with necrotrophic effectors ToxA and ToxB.BMC biology · 2022Article
- Infection Process and Genome Assembly Provide Insights into the Pathogenic Mechanism of Destructive MycoparasiteJournal of fungi (Basel, Switzerland) · 2021Article
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Authors and funding
14 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many microorganisms with specialized lifestyles have reduced genomes. This is best understood in beneficial bacterial symbioses, where partner fidelity facilitates loss of genes necessary for living independently. Specialized microbial pathogens may also exhibit gene loss relative to generalists. Here, we demonstrate that Escovopsis weberi, a fungal parasite of the crops of fungus-growing ants, has a reduced genome in terms of both size and gene content relative to closely related but less specialized fungi. Although primary metabolism genes have been retained, the E. weberi genome is depleted in carbohydrate active enzymes, which is consistent with reliance on a host with these functions. E. weberi has also lost genes considered necessary for sexual reproduction. Contrasting these losses, the genome encodes unique secondary metabolite biosynthesis clusters, some of which include genes that exhibit up-regulated expression during host attack. Thus, the specialized nature of the interaction between Escovopsis and ant agriculture is reflected in the parasite's genome.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.