Evidence map›Paper›PMID 26976392›Full record

ReviewCritical care (London, England)2016

Detrimental cross-talk between sepsis and acute kidney injury: new pathogenic mechanisms, early biomarkers and targeted therapies.

Sergio Dellepiane, Marita Marengo, Vincenzo Cantaluppi

Registry-linked trialAbstract readReview
In one paragraph

Review in Critical care (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03877081 (Effect of Probiotics and Prebiotics in Renal Function in Septic Acute Kidney Injury Patients, Randomized Control Trial), which is not on this map. Cited by 98 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03877081 phase3unknown statusnot on this mapstarted 2019, after this paper: background citation

Effect of Probiotics and Prebiotics in Renal Function in Septic Acute Kidney Injury Patients, Randomized Control Trial

TypeinterventionalSponsorHospital Civil de GuadalajaraRan2019 to 2023Enrolled90ConditionsAcute Kidney Injury, Probiotics, SepsisArmsProbiotics, Placebo
3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sergio DellepianeDepartment of Medical Science, Turin University, AOU Città Della Salute e Della Scienza, Turin, Italy.
Marita MarengoASLCN1, S.C. Nefrologia e Dialisi, Dipartimento Area Medica, Cuneo, Italy.
Vincenzo CantaluppiDepartment of Translational Medicine, University of Eastern Piedmont, "Maggiore della Carità" University Hospital, Novara, Italy. vincenzo.cantaluppi@med.uniupo.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency medicine 2016. Other selected articles can be found online at http://www.biomedcentral.com/collections/annualupdate2016. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901.

Indexed as

Disease ProgressionAcute Kidney InjuryBiomarkersCritical CareHumansIntensive Care UnitsSepsisBiomarkers

Identifiers

PMID26976392
PMCPMC4792098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.