Evidence map›Paper›PMID 26976135›Full record

ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2018

Inhibitory Selection Mechanisms in Clinically Healthy Older and Younger Adults.

Teal S Eich, Beatriz M M Gonçalves, Derek E Nee, Qolamreza Razlighi, John Jonides, Yaakov Stern

Abstract read
In one paragraph

Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  5. Age, Sex, and Inhibitory Control: Identifying a Specific Impairment in Memorial, But Not Perceptual, Inhibition in Older Women.The journals of gerontology. Series B, Psychological sciences and social sciences · 2021
    Article
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  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Teal S EichCognitive Neuroscience Division, Department of Neurology and the Taub Institute, Columbia University Medical Center, New York.
Beatriz M M GonçalvesCognitive Neuroscience Division, Department of Neurology and the Taub Institute, Columbia University Medical Center, New York.
Derek E NeeHelen Wills Neuroscience Institute, University of California, Berkeley.
Qolamreza RazlighiCognitive Neuroscience Division, Department of Neurology and the Taub Institute, Columbia University Medical Center, New York.
John JonidesDepartment of Psychology, University of Michigan, Ann Arbor.
Yaakov SternCognitive Neuroscience Division, Department of Neurology and the Taub Institute, Columbia University Medical Center, New York.

Funding

Imaging of Cognition, Learning and Memory in AgingR01AG026158 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI STERN, YAAKOV · 2004 to 2021
$10.9M
Research Training in Late-Life NeuroPsychiatric DisordersT32MH020004 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Patrick J Brown · 1998 to 2026
$6.1M
Analyzing age-related changes of brain activation in subjects native spaceK01AG044467 · NIA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI RAZLIGHI, QOLAMREZA RAY · 2013 to 2017
$636k
NIA NIH HHS K01 AG044467NIA NIH HHS R01 AG026158NIMH NIH HHS T32 MH020004
6 · The paper itself

Abstract

Objective: Declines in working memory are a ubiquitous finding within the cognitive-aging literature. A unitary inhibitory selection mechanism that serves to guide attention toward task-relevant information and resolve interference from task-irrelevant information has been proposed to underlie such deficits. However, inhibition can occur at multiple time points in the memory-processing stream. Here, we tested whether the time point at which inhibition occurs in the memory-processing stream affects age-related memory decline. Method: Clinically healthy younger (n = 23) and older (n = 22) adults performed two similar item-recognition working memory tasks. In one task, participants received an instruction cue telling them which words to attend to followed by a memory set, promoting perceptual inhibition at the time of encoding. In the other task, participants received the instruction cue after they received the memory set, fostering inhibition of items already in memory. Results: We found that older and younger adults differed in their ability to inhibit items both during encoding and when items had to be inhibited in memory but that these age differences were exaggerated when irrelevant information had to be inhibited from memory. These results provide insights into the mechanisms that support cognitive changes to memory processes in healthy aging.

Indexed as

Inhibition, PsychologicalAdultAgedAge FactorsCognitive DysfunctionCuesFemaleHumansMaleMemory DisordersMemory, Short-TermMiddle AgedReaction TimeRecognition, PsychologyYoung Adult

Identifiers

PMID26976135
PMCPMC6018930

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.