Evidence map›Paper›PMID 26976032›Full record

ArticleClinical and experimental otorhinolaryngology2016

Metastases of Melanoma to Head and Neck Mucosa: A Report of Short Series.

Raphaela Silva Leandro Santos, Marília Ferreira Andrade, Fábio de Abreu Alves, Luiz Paulo Kowalski, Danyel Elias da Cruz Perez

Open access · goldAbstract read
In one paragraph

Article in Clinical and experimental otorhinolaryngology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Raphaela Silva Leandro SantosDepartment of Clinical and Preventive Dentistry, Oral Pathology Section, School of Dentistry, Federal University of Pernambuco, Recife, Brazil.
Marília Ferreira AndradeDepartment of Stomatology, A. C. Camargo Cancer Center, São Paulo, Brazil ; Department of Otorhinolaryngology-Head and Neck Surgery, A. C. Camargo Cancer Center, São Paulo, Brazil.
Fábio de Abreu AlvesDepartment of Stomatology, A. C. Camargo Cancer Center, São Paulo, Brazil ; Department of Otorhinolaryngology-Head and Neck Surgery, A. C. Camargo Cancer Center, São Paulo, Brazil.
Luiz Paulo KowalskiDepartment of Stomatology, A. C. Camargo Cancer Center, São Paulo, Brazil ; Department of Otorhinolaryngology-Head and Neck Surgery, A. C. Camargo Cancer Center, São Paulo, Brazil.
Danyel Elias da Cruz PerezDepartment of Clinical and Preventive Dentistry, Oral Pathology Section, School of Dentistry, Federal University of Pernambuco, Recife, Brazil.
AC Camargo Hospital · BRUniversidade Federal de Pernambuco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMetastasis of melanoma to the head and neck mucosa is a very unusual condition. The aim of this study was to report four cases of patients with metastatic melanoma in the head and neck mucosa treated at a single institution.

methodsClinical data were obtained from the medical records. All cases were histologically reviewed to confirm the diagnosis, and immunohistochemical reactions were performed in the cases submitted to biopsy.

resultsAll patients were males and the mean age was 40.5 years old. The sites of the metastatic tumors were gingival mucosa, floor of the mouth, oropharynx, and larynx. Two tumors appeared as submucosal nodules with normal color; one lesion was a blackish nodular lesion, and one was shown to be an ulcerated lesion. The size of tumors ranged from 2.0 to 4.0 cm. All patients had developed systemic disease at time of diagnosis of metastatic tumor in the head and neck mucosa. Survival rates ranged from 2 to 19 months after the diagnosis of the metastatic mucosal melanoma in the head and neck region.

conclusionAlthough rare, patients with melanoma must be closely and regularly followed up, with careful routine examination of head and neck, because metastatic tumors in this region seem to be part of a lethal widespread metastatic disease.

Indexed as

Head and Neck NeoplasmsMelanomaMouthMucous MembraneNeoplasm Metastasis

Identifiers

PMID26976032
PMCPMC4792238
OpenAlexW2298263390

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.