Evidence map›Paper›PMID 26976029›Full record

ArticleClinical and experimental otorhinolaryngology2016

Prognostic Impact of Ultrasonography Features and (18)F-Fluorodeoxyglucose Uptake in Patients With Papillary Thyroid Microcarcinoma.

Ji Won Seo, Sang Hyun Hwang, Arthur Cho, Hye Sun Lee, Eun-Kyung Kim, Hee Jung Moon, Jung Hyun Yoon, Jin Young Kwak

Open access · goldAbstract read
In one paragraph

Article in Clinical and experimental otorhinolaryngology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Relationship BetweenWorld journal of surgery · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ji Won SeoDepartment of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea.
Sang Hyun HwangDivision of Nuclear Medicine, Department of Radiology, Yonsei University College of Medicine, Seoul, Korea.
Arthur ChoDivision of Nuclear Medicine, Department of Radiology, Yonsei University College of Medicine, Seoul, Korea.
Hye Sun LeeDepartment of Research Affairs, Biostatistics Collaboration Unit, Yonsei University College of Medicine, Seoul, Korea.
Eun-Kyung KimDepartment of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea.
Hee Jung MoonDepartment of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea.
Jung Hyun YoonDepartment of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea.
Jin Young KwakDepartment of Radiology, Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, Korea.
Yonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the prognostic impact of ultrasonography (US) features and (18)F-fluorodeoxyglucose ((18)F-FDG) uptake in patients with papillary thyroid microcarcinoma (PTMC).

methodsThis study included 74 patients with a single PTMC diagnosed pathologically. Patients underwent total thyroidectomy, or near-total thyroidectomy and staging thyroid US and positron emission tomography (PET) were performed prior to surgery. US features of thyroid nodules were reviewed retrospectively and the maximum standard uptake value (SUV) of nodules was semiquantitatively analyzed on (18)F-FDG PET/computed tomography (CT). Patients were followed-up for recurrence, which was defined as PTC on cytology results, elevated serum thyroglobulin (Tg) or anti-Tg antibody levels, or uptake on whole-body scintigraphy. We used univariate and multivariate analyses to evaluate whether poor prognostic outcomes were associated with US features or SUV values derived from PET/CT of nodules. In addition, subjects were divided into 2 groups for subgroup analyses: one with nodules equal to or larger than 5 mm and one with nodules smaller than 5 mm.

resultsAmong the 74 patients, there was no recurrence. Thus we evaluated the correlation between SUV value and US features with poor prognostic factors of PTMC which included extrathyroid extension, central and lateral lymph node (LN) metastasis. However no clinicopathologic factors were associated with extrathyroid extension, central LN metastasis, or lateral LN metastasis.

conclusionIn patients with PTMC, US features and SUV values on FDG-PET were not related to extrathyroid extension or LN metastasis. However, future studies with a larger sample size and longer follow-up should be performed to verify the results of this study.

Indexed as

Papillary Thyroid MicrocarcinomaPositron Emission TomographyThyroidUltrasonography

Identifiers

PMID26976029
PMCPMC4792236
OpenAlexW2299236293

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.