Evidence map›Paper›PMID 26975941›Full record

ArticleJournal of cardiac failure2016

The Obesity and Heart Failure Epidemics Among African Americans: Insights From the Jackson Heart Study.

Arun Krishnamoorthy, Melissa A Greiner, Alain G Bertoni, Zubin J Eapen, Emily C O'Brien, Lesley H Curtis, Adrian F Hernandez, Robert J Mentz

Abstract read
In one paragraph

Article in Journal of cardiac failure, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Examining Community Engagement Research Strategies Used in Flint, Michigan: The Church Challenge.Progress in community health partnerships : research, education, and action · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Arun KrishnamoorthyDuke Clinical Research Institute, Durham, North Carolina; Department of Medicine, Duke University School of Medicine, Durham, North Carolina. Electronic address: arun.krishnamoorthy@duke.edu.
Melissa A GreinerDuke Clinical Research Institute, Durham, North Carolina.
Alain G BertoniDepartment of Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Zubin J EapenDuke Clinical Research Institute, Durham, North Carolina; Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
Emily C O'BrienDuke Clinical Research Institute, Durham, North Carolina; Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
Lesley H CurtisDuke Clinical Research Institute, Durham, North Carolina; Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
Adrian F HernandezDuke Clinical Research Institute, Durham, North Carolina; Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
Robert J MentzDuke Clinical Research Institute, Durham, North Carolina; Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
Clinical Research Institute · USDuke University · USWake Forest University · US

Funding

A Collaboration for Improving Outcomes of African Americans with Heart FailureR01HL117305 · NHLBI · DUKE UNIVERSITY · PI CURTIS, LESLEY H, O'BRIEN, EMILY C · 2013 to 2016
$963k
Targeted Analyses of Jackson Heart Study DataR01HL117285 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BERTONI, ALAIN GERALD · 2013 to 2016
$941k
NHLBI NIH HHS HHSN268201300046CNHLBI NIH HHS HHSN268201300047CNHLBI NIH HHS HHSN268201300048CNHLBI NIH HHS HHSN268201300049CNHLBI NIH HHS HHSN268201300050CNHLBI NIH HHS R01 HL117285NHLBI NIH HHS R01 HL117305
6 · The paper itself

Abstract

backgroundHigher rates of obesity and heart failure have been observed in African Americans, but associations with mortality are not well-described. We examined intermediate and long-term clinical implications of obesity in African Americans and associations between obesity and all-cause mortality, heart failure, and heart failure hospitalization. METHODS AND

resultsWe conducted a retrospective analysis of a community sample of 5292 African Americans participating in the Jackson Heart Study between September 2000 and January 2013. The main outcomes were associations between body mass index (BMI) and all-cause mortality at 9 years and heart failure hospitalization at 7 years using Cox proportional hazards models and interval development of heart failure (median 8 years' follow-up) using a modified Poisson model. At baseline, 1406 (27%) participants were obese and 1416 (27%) were morbidly obese. With increasing BMI, the cumulative incidence of mortality decreased (P= .007), whereas heart failure increased (P < .001). Heart failure hospitalization was more common among morbidly obese participants (9.0%; 95% confidence interval [CI] 7.6-11.7) than among normal-weight patients (6.3%; 95% CI 4.7-8.4). After risk adjustment, BMI was not associated with mortality. Each 1-point increase in BMI was associated with a 5% increase in the risk of heart failure (hazard ratio 1.05; 95% CI 1.03-1.06; P < .001) and the risk of heart failure hospitalization for BMI greater than 32 kg/m(2) (hazard ratio 1.05; 95% CI 1.03-1.07; P < .001).

conclusionsObesity and morbid obesity were common in a community sample of African Americans, and both were associated with increased heart failure and heart failure hospitalization.

Indexed as

Black or African AmericanBody Mass IndexHealthcare DisparitiesRisk AssessmentAdultAgedCause of DeathFemaleFollow-Up StudiesHeart FailureHospitalizationHumansMaleMiddle AgedNorth CarolinaObesity, MorbidHealth care disparitiesheart failureobesity

Identifiers

PMID26975941
PMCPMC4967003
OpenAlexW2295396004

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.