Evidence map›Paper›PMID 26975806›Full record

ArticleScientific reports2016

Chemistry supports the identification of gender-specific reproductive tissue in Tyrannosaurus rex.

Mary Higby Schweitzer, Wenxia Zheng, Lindsay Zanno, Sarah Werning, Toshie Sugiyama

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  10. Identifying medullary bone in extinct avemetatarsalians: challenges, implications and perspectives.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
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  11. Growing upScience advances · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mary Higby SchweitzerDepartment of Biological Sciences, North Carolina State University, Raleigh NC 27695, USA.
Wenxia ZhengDepartment of Biological Sciences, North Carolina State University, Raleigh NC 27695, USA.
Lindsay ZannoDepartment of Biological Sciences, North Carolina State University, Raleigh NC 27695, USA.
Sarah WerningDepartment of Anatomy, Des Moines University, Des Moines IA 50312, USA.
Toshie SugiyamaDepartment of Agrobiology, Niigata University, Niigata 9502181, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medullary bone (MB), an estrogen-dependent reproductive tissue present in extant gravid birds, is texturally, histologically and compositionally distinct from other bone types. Phylogenetic proximity led to the proposal that MB would be present in non-avian dinosaurs, and recent studies have used microscopic, morphological, and regional homologies to identify this reproductive tissue in both theropod and ornithischian dinosaurs. Here, we capitalize on the unique chemical and histological fingerprint of MB in birds to characterize, at the molecular level, MB in the non-avian theropod Tyrannosaurus rex (MOR 1125), and show that the retention of original molecular components in fossils allows deeper physiological and evolutionary questions to be addressed.

Indexed as

AnimalsBone and BonesChickensDinosaursFemaleFossilsKeratan SulfateReproductionSex CharacteristicsSex Determination AnalysisStruthioniformesKeratan Sulfate

Identifiers

PMID26975806
PMCPMC4791554

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.