Evidence map›Paper›PMID 26975718›Full record

ArticleBMC public health2016

Implementation challenges and opportunities for HIV Treatment as Prevention (TasP) among young men in Vancouver, Canada: a qualitative study.

Rod Knight, Will Small, Kim Thomson, Mark Gilbert, Jean Shoveller

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
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  8. Article
  9. The aspirational necessity of HIV prevention.Journal of the International AIDS Society · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Rod KnightFaculty of Health Sciences, Simon Fraser University, Burnaby, Canada.ORCID http://orcid.org/0000-0002-1464-1584
Will SmallFaculty of Health Sciences, Simon Fraser University, Burnaby, Canada.
Kim ThomsonSchool of Population and Public Health, University of British Columbia, 2206 East Mall, Vancouver, British Columbia, V6T 1Z3, Canada.
Mark GilbertSchool of Population and Public Health, University of British Columbia, 2206 East Mall, Vancouver, British Columbia, V6T 1Z3, Canada.
Jean ShovellerSchool of Population and Public Health, University of British Columbia, 2206 East Mall, Vancouver, British Columbia, V6T 1Z3, Canada. jean.shoveller@ubc.ca.
University of British Columbia · CASimon Fraser University · CA

Funding

Vancouver Drug Users Study: The Impacts of Evolving Drug Use Patterns on HIV/AIDSU01DA038886 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI DEBECK, KORA, HAYASHI, KANNA · 2015 to 2024
$12.1M
Initiation of injection drug use and HIV risks among street-involved youthR01DA028532 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI WOOD, EVAN · 2010 to 2014
$1.9M
HIV Risk Environments among FSW and DU: A Longitudinal Ethno-Spatial ApproachR01DA033147 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI KERR, THOMAS, SHANNON, KATE · 2012 to 2016
$1.8M
Canadian Institutes of Health Research EPP-122906Canadian Institutes of Health Research HHP-123778NIDA NIH HHS R01 DA028532NIDA NIH HHS R01DA028532NIDA NIH HHS R01 DA033147NIDA NIH HHS R01DA033147NIDA NIH HHS U01 DA038886NIDA NIH HHS U01DA038886
6 · The paper itself

Abstract

backgroundDespite evidence supporting the preventative potential of HIV Treatment as Prevention (TasP), scientific experts and community stakeholders have suggested that the success of TasP at the population level will require overcoming a set of complex and population-specific implementation challenges. For example, the factors that might influence decisions to initiate 'early' treatment have yet to be thoroughly understood; neither have questions about the factors that enhance or impede their ability to achieve long-term adherence to ARVs or the social norms regarding various treatment regimens been examined in detail. This knowledge gap may hamper opportunities to effectively develop public health practices that are informed by the various challenges and opportunities related to TasP implementation and scale up.

methodsDrawing on 50 in-depth, individual interviews with young men ages 18-24 in Vancouver, Canada, this study examines young men's perspectives regarding factors that might affect their engagement with TasP.

resultsWhile findings from the current study indicate young men generally have a high receptiveness to TasP, our findings also identify key social and structural forces that will warrant ongoing consideration for TasP implementation. For example, participants described how an enhanced awareness regarding treatment (including awareness of the universal availability of treatment in Vancouver) would be a necessary, but not sufficient, condition to decide to endorse TasP. Their decisions about engaging in HIV care in the context of TasP (e.g., HIV testing, treatment initiation, long-term adherence) also appear to be contingent on their ability to negotiate or 'balance' the risks and benefits to themselves and others. The findings also offer insight into the complex and sometimes controversial narratives that continue to emerge regarding risk compensation practices in the context of TasP.

conclusionBased on the results of this study, we identify several areas that hold promise for informing the effective scale up of TasP, including new information regarding implementation adaptation strategies.

Indexed as

AdolescentAwarenessCanadaHIV InfectionsHumansInterviews as TopicMaleMedication AdherencePre-Exposure ProphylaxisPublic HealthQualitative ResearchYoung AdultCanadaHIV/AIDSTreatment as preventionYoung men

Identifiers

PMID26975718
PMCPMC4791765
OpenAlexW2298443507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.