Evidence map›Paper›PMID 26975559›Full record

ArticleEnvironmental science & technology2016

Measuring Personal Exposure to Organophosphate Flame Retardants Using Silicone Wristbands and Hand Wipes.

Stephanie C Hammel, Kate Hoffman, Thomas F Webster, Kim A Anderson, Heather M Stapleton

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Environmental science & technology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 102 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 2 pooled it
17.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 2 syntheses or guidelines pooled it, 208 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  5. Review
  6. Article
  7. Article
  8. Silicone Wristbands for Measuring Human Exposure to Organic Chemicals: Uses and Benefits for Human Biological Research.American journal of human biology : the official journal of the Human Biology Council · 2026
    Article
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  19. PMGeoHealth · 2024
    Article
  20. Investigation ofCurrent research in toxicology · 2024
    Article

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Stephanie C HammelNicholas School of the Environment, Duke University , Durham, North Carolina 27708, United States.
Kate HoffmanNicholas School of the Environment, Duke University , Durham, North Carolina 27708, United States.
Thomas F WebsterDepartment of Environmental Health, Boston University School of Public Health , Boston, Massachusetts 02118, United States.
Kim A AndersonDepartment of Environmental and Molecular Toxicology, Oregon State University , Corvallis, Oregon 97331, United States.
Heather M StapletonNicholas School of the Environment, Duke University , Durham, North Carolina 27708, United States.
Duke University · USBoston University · USOregon State University · US

Funding

Research Experience and Training Coordination CoreP42ES016465 · NIEHS · OREGON STATE UNIVERSITY · PI Susan C Tilton · 2009 to 2026
$52.5M
Children's Exposure to Flame Retardants: Effects on Thyroid Hormone RegulationR01ES016099 · NIEHS · DUKE UNIVERSITY · PI STAPLETON, HEATHER M · 2008 to 2017
$5.0M
NIEHS NIH HHS P42 ES016465NIEHS NIH HHS R01 ES016099NIEHS NIH HHS R01ES016099
6 · The paper itself

Abstract

Organophosphate flame retardants (PFRs) are widely used as replacements for polybrominated diphenyl ethers in consumer products. With high detection in indoor environments and increasing toxicological evidence suggesting a potential for adverse health effects, there is a growing need for reliable exposure metrics to examine individual exposures to PFRs. Silicone wristbands have been used as passive air samplers for quantifying exposure in the general population and occupational exposure to polycyclic aromatic hydrocarbons. Here we investigated the utility of silicone wristbands in measuring exposure and internal dose of PFRs through measurement of urinary metabolite concentrations. Wristbands were also compared to hand wipes as metrics of exposure. Participants wore wristbands for 5 consecutive days and collected first morning void urine samples on 3 alternating days. Urine samples were pooled across 3 days and analyzed for metabolites of the following PFRs: tris(1,3-dichloroisopropyl) phosphate (TDCIPP), tris(1-chloro-2-isopropyl) phosphate (TCIPP), triphenyl phosphate (TPHP), and monosubstituted isopropylated triaryl phosphate (mono-ITP). All four PFRs and their urinary metabolites were ubiquitously detected. Correlations between TDCIPP and TCIPP and their corresponding urinary metabolites were highly significant on the wristbands (rs = 0.5-0.65, p < 0.001), which suggest that wristbands can serve as strong predictors of cumulative, 5-day exposure and may be an improved metric compared to hand wipes.

Indexed as

AdultAir Pollution, IndoorEnvironmental ExposureEnvironmental MonitoringEquipment DesignFemaleFlame RetardantsHandHumansMaleMiddle AgedOrganophosphatesSiliconesSurveys and QuestionnairesFlame RetardantsOrganophosphatesSilicones

Identifiers

PMID26975559
PMCPMC4872512
OpenAlexW2299077788

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.