Evidence map›Paper›PMID 26975327›Full record

ArticleIranian biomedical journal2016

Demonstration of Herpes Simplex Virus, Cytomegalovirus, and Epstein-Barr Virus in Colorectal Cancer.

Sahar Mehrabani-Khasraghi, Mitra Ameli, Farzad Khalily

Open access · greenAbstract read
In one paragraph

Article in Iranian biomedical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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  6. Viruses in colorectal cancer.Molecular oncology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Sahar Mehrabani-KhasraghiDepartment of Microbiology, Tonekabon Branch, Islamic Azad University, Mazandaran, Iran.
Mitra AmeliDepartment of Medicine, Tonekabon Branch, Islamic Azad University, Mazandaran, Iran.
Farzad KhalilyGastroenterology and Hepatology Research Center, Karaj University of Medical Sciences and Health Services, Alborz, Iran.
Islamic Azad University Tonekabon · IRJahrom University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present study sought to investigate molecular evidence for association between the presence of herpes simplex virus (HSV), cytomegalovirus (CMV), and Epstein-Barr virus (EBV) in CRC and colorectal polyp by using the PCR method in Iran.

methodsIn this analytical case-control study, we selected 15 patients with CRC, 20 patients with colorectal polyp, and 35 patients without malignancy as controls. After DNA extraction, PCR was used to determine HSV, CMV, and EBV genome by specific primers. Statistical analysis was performed using χ2 tests.

resultsOur findings demonstrated that there is no direct molecular evidence to support the association between HSV, CMV, and EBV and human colorectal malignancies.

conclusionThe results from this study do not exclude a possible oncogenic role of these viruses in neoplastic development of colon cells.

Indexed as

Case-Control StudiesColonic PolypsColorectal NeoplasmsCytomegalovirusDNA PrimersDNA, ViralHerpesvirus 4, HumanHumansPolymerase Chain ReactionSimplexvirusDNA PrimersDNA, ViralColorectal cancerCytomegalovirusEpstein-Bar virusHerpes simplex virusPCR

Identifiers

PMID26975327
PMCPMC5075144
OpenAlexW2300749955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.