Evidence map›Paper›PMID 26974799›Full record

ArticleApplied optics2016

Automated interferometric synthetic aperture microscopy and computational adaptive optics for improved optical coherence tomography.

Yang Xu, Yuan-Zhi Liu, Stephen A Boppart, P Scott Carney

Abstract read
In one paragraph

Article in Applied optics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yang Xu
Yuan-Zhi Liu
Stephen A Boppart
P Scott Carney

Funding

Intraoperative Label-Free Optical Molecular Imaging of Breast Tumor MarginsR01CA166309 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, STEPHEN A · 2012 to 2016
$2.5M
Intraoperative Polarization-Sensitive OCT for Assessing Breast Tumor MarginsR01CA213149 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BOPPART, STEPHEN A · 2017 to 2021
$2.4M
Howard Hughes Medical InstituteNCI NIH HHS 1 R01 CA166309NCI NIH HHS HHSN261201400044CNCI NIH HHS R01 CA166309NCI NIH HHS R01 CA213149PHS HHS HHSN261201400044C
6 · The paper itself

Abstract

In this paper, we introduce an algorithm framework for the automation of interferometric synthetic aperture microscopy (ISAM). Under this framework, common processing steps such as dispersion correction, Fourier domain resampling, and computational adaptive optics aberration correction are carried out as metrics-assisted parameter search problems. We further present the results of this algorithm applied to phantom and biological tissue samples and compare with manually adjusted results. With the automated algorithm, near-optimal ISAM reconstruction can be achieved without manual adjustment. At the same time, the technical barrier for the nonexpert using ISAM imaging is also significantly lowered.

Indexed as

AlgorithmsAutomationHumansMicroscopy, InterferenceOptics and PhotonicsPhantoms, ImagingSkinTomography, Optical Coherence

Identifiers

PMID26974799
PMCPMC5458786

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.