ReviewCancer metastasis reviews1989
Carcinoembryonic antigen: function in metastasis by human colorectal carcinoma.
Review in Cancer metastasis reviews, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 91 citations in OpenAlex.
- Blood and Saliva Composition in Cancer: Similarities or Differences?Current issues in molecular biology · 2026Review
- Carcinoembryonic Antigen (CEA): Origin, Role in Oncology, and Concentrations in Serum and Peritoneal Fluid.Journal of clinical medicine · 2025Review
- Assessing the potential relevance of CEACAM6 as a blood transcriptional biomarker.F1000Research · 2022Article
- Epithelial Cell Adhesion Molecule mRNA Can be a Potential Marker to Predict Metastasis in Hepatocellular Carcinoma Patients.Asian Pacific journal of cancer prevention : APJCP · 2020Article
- Significant association of PRMT6 hypomethylation with colorectal cancer.Journal of clinical laboratory analysis · 2018Article
- The role ofOncotarget · 2017Article
- Accessing new prognostic significance of preoperative carcinoembryonic antigen in colorectal cancer receiving tumor resection: More than positive and negative.Cancer biomarkers : section A of Disease markers · 2017Article
- Selecting Tumor-Specific Molecular Targets in Pancreatic Adenocarcinoma: Paving the Way for Image-Guided Pancreatic Surgery.Molecular imaging and biology · 2016Article
- Diagnostic value of preoperative serum carcinoembryonic antigen and carbohydrate antigen 19-9 in colorectal cancer.Current oncology (Toronto, Ont.) · 2014Article
- Carcinoembryonic antigen antibody inhibits lung metastasis and augments chemotherapy in a human colonic carcinoma xenograft.Cancer immunology, immunotherapy : CII · 2005Article
- Expression of cell adhesion molecules in oesophageal carcinoma and its prognostic value.Journal of clinical pathology · 2005Review
- Carcinoembryonic antigen facilitates experimental metastasis through a mechanism that does not involve adhesion to liver cells.Clinical & experimental metastasis · 1999Article
- Growth inhibition, enhancement of intercellular adhesion, and increased expression of carcinoembryonic antigen by overexpression of phosphoinositides-specific phospholipase C beta 1 in LS174T human colon adenocarcinoma cell line.Japanese journal of cancer research : Gann · 1998Article
- Inhibition of human HT-29 colon carcinoma cell adhesion by a 4-fluoro-glucosamine analogue.Glycoconjugate journal · 1996Article
- The role of cell adhesion molecules and proteases in tumor invasion and metastasis.World journal of urology · 1996Review
- [Protein-carbohydrate recognition. Foundation and medical application with illustrations of tumor lectin studies].Die Naturwissenschaften · 1995Review
- Augmentation of carcinoembryonic antigen release from intact, viable tumor cells by a factor in human serum.Annals of surgical oncology · 1995Article
- Characterization of a family of structurally related glycoproteins expressing beta 1-6-branched asparagine-linked oligosaccharides in human colon carcinoma cells.The Biochemical journal · 1992Article
- Metastatic potential of human colon cancer cell lines: relationship to cellular differentiation and carcinoembryonic antigen production.Clinical & experimental metastasis · 1992Article
- Induction of carcinoembryonic-antigen-gene expression in human colorectal carcinoma by sodium butyrate.The Biochemical journal · 1990Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Carcinoembryonic antigen (CEA) is a glycoprotein that has been useful as a tumor marker to predict recurrence in gastrointestinal malignancies, but whose biological function has not been elucidated. With the recent evidence that CEA is a member of the immunoglobulin supergene family, CEA may be involved in intercellular recognition and binding. This review examines the role that CEA plays in the development of metastases by colorectal carcinoma.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.