ArticleOrganic letters2016
Synthesis of Rumphellaone A and Hushinone by a Gold-Catalyzed [2 + 2] Cycloaddition.
Article in Organic letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Gold(I)-Catalyzed Intermolecular Reactions of Alkynes with Carbon Nucleophiles: What We Knowand What We Don't.ACS catalysis · 2026Review
- Recent advances in enyne cycloisomerization using N-heterocyclic carbene gold complexes.RSC advances · 2025Review
- Total Synthesis of Terpenes and Their Biological Significance: A Critical Review.Pharmaceuticals (Basel, Switzerland) · 2022Review
- New-Generation Ligand Design for the Gold-Catalyzed Asymmetric Activation of Alkynes.ChemPlusChem · 2021Review
- Gold-Catalyzed Synthesis of Small Rings.Chemical reviews · 2021Article
- Novel Caryophyllane-Related Sesquiterpenoids with Anti-Inflammatory Activity fromMarine drugs · 2020Article
- Recent advances in the synthesis of gem-dimethylcyclobutane natural products.Natural product reports · 2019Review
- Metal-free alkene carbooxygenation following tandem intramolecular alkoxylation/Claisen rearrangement: stereocontrolled access to bridged [4.2.1] lactones.Chemical science · 2019Article
- A modular approach to prepare enantioenriched cyclobutanes: synthesis of (+)-rumphellaone A.Chemical science · 2019Article
- Synthesis of (-)-Hebelophyllene E: An Entry to Geminal Dimethyl-Cyclobutanes by [2+2] Cycloaddition of Alkenes and Allenoates.Angewandte Chemie (International ed. in English) · 2018Article
- Role of σ,π-Digold(I) Alkyne Complexes in Reactions of Enynes.Organometallics · 2018Article
- Enantioselective Synthesis of Cyclobutenes by Intermolecular [2+2] Cycloaddition with Non-CJournal of the American Chemical Society · 2017Article
- Cyclobutene vs 1,3-Diene Formation in the Gold-Catalyzed Reaction of Alkynes with Alkenes: The Complete Mechanistic Picture.Journal of the American Chemical Society · 2017Article
- Gold-Catalyzed Vinyl Ether Hydroalkynylation: An Alternative Pathway for the Gold-Catalyzed Intermolecular Reaction of Alkenes and Alkynes.Organic letters · 2016Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The enantioselective total synthesis of rumphellaone A has been accomplished in 12 steps via a diastereoselective gold(I)-catalyzed [2 + 2] macrocyclization of a 1,10-enyne as the key step to build the cyclobutene moiety. This concise approach has also led to the total synthesis of husinone.
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