ArticleScience advances2016
Host-parasite Red Queen dynamics with phase-locked rare genotypes.
Article in Science advances, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- In silico prediction method for plant Nucleotide-binding leucine-rich repeat- and pathogen effector interactions.The Plant journal : for cell and molecular biology · 2025Article
- Geography, phylogeny and host switch drive the coevolution of parasitic Gyrodactylus flatworms and their hosts.Parasites & vectors · 2024Article
- Nature-Inspired Intelligent Computing: A Comprehensive Survey.Research (Washington, D.C.) · 2024Review
- Transgenerational genomic analyses reveal allelic oscillation and purifying selection in a gut parasiteFrontiers in microbiology · 2022Article
- Spillover and genome selection of the gut parasiteFrontiers in cellular and infection microbiology · 2022Article
- What lies behind the curtain: Cryptic diversity in helminth parasites of human and veterinary importance.Current research in parasitology & vector-borne diseases · 2022Review
- Balancing Selection for Pathogen Resistance Reveals an Intercontinental Signature of Red Queen Coevolution.Molecular biology and evolution · 2021Article
- Higher mortality of the less suitable brown trout host compared to the principal Atlantic salmon host when infested with freshwater pearl mussel (Margaritifera margaritifera) glochidia.Parasitology research · 2021Article
- Continual evolution through coupled fast and slow feedbacks.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- How long do Red Queen dynamics survive under genetic drift? A comparative analysis of evolutionary and eco-evolutionary models.BMC evolutionary biology · 2020Article
- Neutral genomic signatures of host-parasite coevolution.BMC evolutionary biology · 2019Article
- Antibiotic-driven escape of host in a parasite-induced Red Queen dynamics.Royal Society open science · 2018Article
- Malaria parasites of long-tailed macaques in Sarawak, Malaysian Borneo: a novel species and demographic and evolutionary histories.BMC evolutionary biology · 2018Article
- A generalized population dynamics model for reproductive interference with absolute density dependence.Scientific reports · 2017Article
- Ruminant-specific multiple duplication events of PRDM9 before speciation.BMC evolutionary biology · 2017Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Interactions between hosts and parasites have been hypothesized to cause winnerless coevolution, called Red Queen dynamics. The canonical Red Queen dynamics assume that all interacting genotypes of hosts and parasites undergo cyclic changes in abundance through negative frequency-dependent selection, which means that any genotype could become frequent at some stage. However, this prediction cannot explain why many rare genotypes stay rare in natural host-parasite systems. To investigate this, we build a mathematical model involving multihost and multiparasite genotypes. In a deterministic and controlled environment, Red Queen dynamics occur between two genotypes undergoing cyclic dominance changes, whereas the rest of the genotypes remain subordinate for long periods of time in phase-locked synchronized dynamics with low amplitude. However, introduction of stochastic noise in the model might allow the subordinate cyclic host and parasite types to replace dominant cyclic types as new players in the Red Queen dynamics. The factors that influence such evolutionary switching are interhost competition, specificity of parasitism, and degree of stochastic noise. Our model can explain, for the first time, the persistence of rare, hardly cycling genotypes in populations (for example, marine microbial communities) undergoing host-parasite coevolution.
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