Evidence map›Paper›PMID 26973830›Full record

ArticleFrontiers in chemistry2016

Surface Analysis of Gold Nanoparticles Functionalized with Thiol-Modified Glucose SAMs for Biosensor Applications.

Valentina Spampinato, Maria Antonietta Parracino, Rita La Spina, Francois Rossi, Giacomo Ceccone

Abstract read
In one paragraph

Article in Frontiers in chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

  1. Article
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  3. Monosaccharide-Derived Enantioselectivity in SWCNT Chemoresistive VOC Sensing.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
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  11. Fabrication and Functionalisation of Nanocarbon-Based Field-Effect Transistor Biosensors.Chembiochem : a European journal of chemical biology · 2022
    Review
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  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Valentina SpampinatoEuropean Commission, Joint Research Centre, Institute for Health and Consumer ProtectionIspra, Italy; Istituto di Fisica dei Plasmi, Consiglio Nazionale delle RicercheMilano, Italy.
Maria Antonietta ParracinoEuropean Commission, Joint Research Centre, Institute for Health and Consumer ProtectionIspra, Italy; Technical Department, Nanoimmunotech S.LZaragoza, Spain.
Rita La SpinaEuropean Commission, Joint Research Centre, Institute for Health and Consumer Protection Ispra, Italy.
Francois RossiEuropean Commission, Joint Research Centre, Institute for Health and Consumer Protection Ispra, Italy.
Giacomo CecconeEuropean Commission, Joint Research Centre, Institute for Health and Consumer Protection Ispra, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, Time of Flight Secondary Ion Mass Spectrometry (ToF-SIMS), Principal Component Analysis (PCA) and X-ray Photoelectron Spectroscopy (XPS) have been used to characterize the surface chemistry of gold substrates before and after functionalization with thiol-modified glucose self-assembled monolayers and subsequent biochemical specific recognition of maltose binding protein (MBP). The results indicate that the surface functionalization is achieved both on flat and nanoparticles gold substrates thus showing the potential of the developed system as biodetection platform. Moreover, the method presented here has been found to be a sound and valid approach to characterize the surface chemistry of nanoparticles functionalized with large molecules. Both techniques were proved to be very useful tools for monitoring all the functionalization steps, including the investigation of the biological behavior of the glucose-modified particles in the presence of the maltose binding protein.

Indexed as

biodetectiongold nanoparticlesSAMssurface functionalizationToF-SIMSXPS

Identifiers

PMID26973830
PMCPMC4770020

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.