Evidence map›Paper›PMID 26973807›Full record

ReviewCureus2016

The Use of Flow Diversion for the Treatment of Intracranial Aneurysms: Expansion of Indications.

Adam M Brouillard, Xingwen Sun, Adnan H Siddiqui, Ning Lin

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
6.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Safety and efficacy profile of off-label use of the Pipeline Embolization Device: A systematic review and meta-analysis.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2024
    Pooled it
  2. Pooled it
  3. Article
  4. Stand-alone small low-profile braided stents for challenging unruptured posterior inferior cerebellar artery aneurysms compared to conventional endovascular methods: A cohort study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Flow diverter stents in the treatment of recanalized intracranial aneurysms.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021
    Article
  11. The p48 flow diverter: First clinical results in 25 aneurysms in three centers.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021
    Article
  12. Article
  13. One and done? The effect of number of Pipeline embolization devices on aneurysm treatment outcomes.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2020
    Article
  14. Review
  15. The Silk Vista Baby: Initial experience and report of two cases.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2019
    Article
  16. Article
  17. Observational
  18. Observational
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Adam M BrouillardDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York.
Xingwen SunDepartment of Neurosurgery, Weill Cornell Medical College ; New York Presbyterian Hospital.
Adnan H SiddiquiDepartment of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York.
Ning LinDepartment of Neurosurgery, Weill Cornell Medical College.
New York Hospital Queens · USJacobs Institute · USWeill Cornell Medical College in Qatar · QA

Funding

Micro-Radiographic Imager for Neuroovascular InterventionsR01EB002873 · NIBIB · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI RUDIN, STEPHEN · 2003 to 2015
$5.6M
Hemodynamic Induction of Pathologic Remodeling Leading to Intracranial AneurysmsR01NS064592 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MENG, HUI · 2009 to 2013
$1.7M
Virtual Intervention of Intracranial AneurysmsR01NS091075 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MENG, HUI · 2015 to 2019
$1.7M
NIBIB NIH HHS R01 EB002873NINDS NIH HHS R01 NS064592NINDS NIH HHS R01 NS091075
6 · The paper itself

Abstract

Flow diversion is a novel concept for treating anatomically challenging intracranial aneurysms and has gained increasing acceptance. Flow diverter stents, such as the Pipeline Embolization Device (PED) (ev3-Covidien, Irvine, CA, USA), are approved for treating unruptured large and giant aneurysms from the internal carotid artery between the superior hypophyseal and cavernous segments. However, technological advances and recent clinical results suggest that flow diversion can be safely and effectively used in treating ruptured aneurysms, posterior circulation aneurysms, and distal anterior circulation aneurysms. In this brief review, we aim to investigate the recent evidence on the utilization of PEDs in these controversial vascular territories and to discuss whether the indications for flow diversion can be expanded.

Indexed as

coil embolizationcomplicationendovascular treatmentflow diversionintracranial aneurysmruptured aneurysm

Identifiers

PMID26973807
PMCPMC4772997
OpenAlexW2289833367

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.