Evidence map›Paper›PMID 26973796›Full record

ArticleJournal of neurology & neurophysiology2015

Reduced Resting Metabolic Rate in Adults with Hemiparetic Chronic Stroke.

Monica C Serra, Charlene E Hafer-Macko, Alice S Ryan

Open access · hybridAbstract read
In one paragraph

Article in Journal of neurology & neurophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Effects of Balance Training Using a Virtual Reality Program in Hemiplegic Patients.International journal of environmental research and public health · 2022
    Article
  3. Review
  4. Review
  5. Review
  6. Increased Energy Cost of Mobility in Chronic Stroke.Journal of gerontology & geriatric research · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Monica C SerraDepartment of Veterans Affairs, Baltimore VAMC, Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, USA.
Charlene E Hafer-MackoDepartment of Veterans Affairs, Baltimore VAMC, Department of Neurology, University of Maryland School of Medicine, Baltimore, USA.
Alice S RyanDepartment of Veterans Affairs, Baltimore VAMC, Division of Gerontology and Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, USA.
University of Maryland, Baltimore · US

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI Stephen L. Seliger · 2006 to 2026
$28.9M
Aging, Inflammation and Exercise in Chronic StrokeR01AG030075 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI HAFER-MACKO, CHARLENE E, RYAN, ALICE S. · 2008 to 2012
$2.4M
Aerobic Training to Improve Energy Utilization and Antioxidant Capacity in StrokeIK2RX000944 · VA · VETERANS HEALTH ADMINISTRATION · PI SERRA, MONICA C · 2014 to 2019
–
NIA NIH HHS P30 AG028747NIA NIH HHS R01 AG030075RRD VA IK2 RX000944
6 · The paper itself

Abstract

objectiveResting metabolic rate (RMR) is the component of energy expenditure that explains the largest proportion of total daily energy requirements. Since RMR is determined largely by fat-free mass and a low RMR predicts weight gain in healthy adults, identifying the role of muscle atrophy following stroke on RMR may help identify ways to mitigate the development of obesity post-stroke.

methodsThirty-nine stroke survivors with chronic hemiparesis (mean ± SEM: age: 61 ± 1 years, latency from stroke: 107 ± 40 months, BMI: 31 ± 3 kg/m2) underwent DXA scans for measurement of body composition, including total, paretic, and non-paretic leg lean mass and fasted, 30-min indirect calorimetry for measurement of RMR.

resultPredicted RMR was calculated by the Mifflin-St Jeor equation, which considers weight, height, and age for both men and women. RMR was 14% lower than predicted (1438 ± 45 vs. 1669 ± 38 kcals/24 hrs; P<0.01). Total (r=0.73, P<0.01), paretic (r=0.72, P<0.01) and non-paretic (r=0.67, P<0.01) leg lean mass predicted RMR.

conclusionThese data indicate that muscle atrophy post stroke may lead to a reduced RMR. This substantiates the need to attenuate the loss of lean mass after a stroke to prevent declines in RMR and possible weight gain common post-stroke.

Indexed as

Chronic strokeResting metabolic rateWeight management

Identifiers

PMID26973796
PMCPMC4786940
OpenAlexW2470436133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.