ArticleFrontiers in plant science2016
Dual RNA-Sequencing of Eucalyptus nitens during Phytophthora cinnamomi Challenge Reveals Pathogen and Host Factors Influencing Compatibility.
Article in Frontiers in plant science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- Pathogenesis-related protein 10 in resistance to biotic stress: progress in elucidating functions, regulation and modes of action.Frontiers in plant science · 2023Pooled it
- Biofilm Source Shapes the Tolerance to Short-Term Ciprofloxacin Exposure.Environmental microbiology reports · 2026Article
- A weighted gene co-expression network analysis characterises the common defence responses of Eucalyptus to diverse biotic challenges.Scientific reports · 2026Article
- Ulmus minor response to Dutch elm disease: de novo transcriptome assembly and annotation.Scientific data · 2025Article
- Transcriptional time-course analysis during ash dieback infection revealed different responses in tolerant and susceptible Fraxinus excelsior genotypes.BMC plant biology · 2025Article
- Preliminary transcriptomic analyses revealFrontiers in microbiology · 2025Article
- An improved method to study Phytophthora cinnamomi Rands zoospores interactions with host.BMC plant biology · 2024Article
- Identification of Phytophthora cinnamomi CRN effectors and their roles in manipulating cell death during Persea americana infection.BMC genomics · 2024Article
- Genome-wide identification of rubber tree pathogenesis-related 10 (PR-10) proteins with biological relevance to plant defense.Scientific reports · 2024Article
- Dual transcriptomic analysis reveals early inducedFrontiers in plant science · 2024Article
- Genomic and transcriptomic analyses ofFrontiers in microbiology · 2024Article
- Genome-wide identification and expression profile analysis of metal tolerance protein gene family in Eucalyptus grandis under metal stresses.BMC plant biology · 2023Article
- Unraveling Plant Cell Death duringMicroorganisms · 2022Review
- European and American chestnuts: An overview of the main threats and control efforts.Frontiers in plant science · 2022Review
- Differences in the Proteomic and Metabolomic Response ofFrontiers in microbiology · 2022Article
- qtlXplorer: an online systems genetics browser in the Eucalyptus Genome Integrative Explorer (EucGenIE).BMC bioinformatics · 2021Article
- Dual transcriptomic analysis reveals metabolic changes associated with differential persistence of human pathogenic bacteria in leaves of Arabidopsis and lettuce.G3 (Bethesda, Md.) · 2021Article
- Plant-Microbe Interaction: Aboveground to Belowground, from the Good to the Bad.International journal of molecular sciences · 2021Review
- Integrative Pre-Breeding for Biotic Resistance in Forest Trees.Plants (Basel, Switzerland) · 2021Review
- Haustorium formation and a distinct biotrophic transcriptome characterize infection of Nicotiana benthamiana by the tree pathogen Phytophthora kernoviae.Molecular plant pathology · 2021Article
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8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Damage caused by Phytophthora cinnamomi Rands remains an important concern on forest tree species. The pathogen causes root and collar rot, stem cankers, and dieback of various economically important Eucalyptus spp. In South Africa, susceptible cold tolerant Eucalyptus plantations have been affected by various Phytophthora spp. with P. cinnamomi considered one of the most virulent. The molecular basis of this compatible interaction is poorly understood. In this study, susceptible Eucalyptus nitens plants were stem inoculated with P. cinnamomi and tissue was harvested five days post inoculation. Dual RNA-sequencing, a technique which allows the concurrent detection of both pathogen and host transcripts during infection, was performed. Approximately 1% of the reads mapped to the draft genome of P. cinnamomi while 78% of the reads mapped to the Eucalyptus grandis genome. The highest expressed P. cinnamomi gene in planta was a putative crinkler effector (CRN1). Phylogenetic analysis indicated the high similarity of this P. cinnamomi CRN1 to that of Phytophthora infestans. Some CRN effectors are known to target host nuclei to suppress defense. In the host, over 1400 genes were significantly differentially expressed in comparison to mock inoculated trees, including suites of pathogenesis related (PR) genes. In particular, a PR-9 peroxidase gene with a high similarity to a Carica papaya PR-9 ortholog previously shown to be suppressed upon infection by Phytophthora palmivora was down-regulated two-fold. This PR-9 gene may represent a cross-species effector target during P. cinnamomi infection. This study identified pathogenicity factors, potential manipulation targets, and attempted host defense mechanisms activated by E. nitens that contributed to the susceptible outcome of the interaction.
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