ArticleFrontiers in plant science2016
Transcriptome Characterization of Gnetum parvifolium Reveals Candidate Genes Involved in Important Secondary Metabolic Pathways of Flavonoids and Stilbenoids.
Article in Frontiers in plant science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 52 citations in OpenAlex.
- MYB30 and MYB14 form a repressor-activator module with WRKY8 that controls stilbene biosynthesis in grapevine.The Plant cell · 2023Article
- Phenolic Contents and Antioxidant Activity ofAntioxidants (Basel, Switzerland) · 2022Article
- Higenamine in Plants as a Source of Unintentional Doping.Plants (Basel, Switzerland) · 2022Review
- Transcriptome Profiling to the Effects of Drought Stress on Different Propagation Modes of Tea Plant (Frontiers in genetics · 2022Article
- Impact of Environmental Factors on Stilbene Biosynthesis.Plants (Basel, Switzerland) · 2021Review
- Comparative Analyses of Full-Length Transcriptomes RevealFrontiers in genetics · 2021Article
- Article
- Combined Metabolome and Transcriptome Analyses Reveal the Effects of Mycorrhizal FungusInternational journal of molecular sciences · 2020Article
- Single-Molecule Long-Read Sequencing Reveals the Diversity of Full-Length Transcripts in Leaves ofInternational journal of molecular sciences · 2019Article
- Screening and Evaluation of Xanthine Oxidase Inhibitors fromMolecules (Basel, Switzerland) · 2019Article
- γ-Aminobutyric acid is closely associated with accumulation of flavonoids.Plant signaling & behavior · 2019Article
- Significance of Photosynthetic Characters in the Evolution of AsianFrontiers in plant science · 2019Article
- Article
- Regulation of stilbene biosynthesis in plants.Planta · 2017Review
- Transcriptomic analyses reveal biosynthetic genes related to rosmarinic acid in Dracocephalum tanguticum.Scientific reports · 2017Article
- Recent studies on resveratrol and its biological and pharmacological activity.EXCLI journal · 2017Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gnetum is a small, unique group of Gnetophyta with a controversial phylogenetic position. Gnetum parvifolium is an important Chinese traditional medicinal plant, which is rich in bioactive compounds such as flavonoids and stilbenoids. These compounds provide significant medicinal effects, mostly as antioxidant, anticancer, and antibacterial agents. However, the mechanisms involved in the biosynthesis and regulation of these compounds in G. parvifolium are still unknown. In this study, we found that flavonoids and stilbene compounds accumulated at different levels in various tissues of G. parvifolium. We further obtained and analyzed massive sequence information from pooled samples of G. parvifolium by transcriptome sequencing, which generated 94,816 unigenes with an average length of 724 bp. Functional annotation of all these unigenes revealed that many of them were associated with several important secondary metabolism pathways including flavonoids and stilbenoids. In particular, several candidate unigenes (PAL-, C4H-, 4CL-, and STS-like genes) involved in stilbenoids biosynthesis were highly expressed in leaves and mature fruits. Furthermore, high temperature and UV-C strongly induced the expression of these genes and enhanced stilbene production (i.e., resveratrol and piceatannol) in leaves of young seedlings. Our present transcriptomic and biochemical data on secondary metabolites in G. parvifolium should encourage further investigation on evolution, ecology, functional genomics, and breeding of this plant with strong pharmaceutical potential.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.