ReviewFrontiers in immunology2016
Human NK Cell Diversity in Viral Infection: Ramifications of Ramification.
Review in Frontiers in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- PolyoxidoniumFrontiers in immunology · 2019Trial
- Natural killer cells: gatekeepers of healthy aging in longevity medicine.Inflammation and regeneration · 2026Review
- Generation of non-genetically modified, CAR-like, NK cells.Journal for immunotherapy of cancer · 2024Article
- NK cells in peripheral blood carry trogocytosed tumor antigens from solid cancer cells.Frontiers in immunology · 2023Article
- Generation and validation of CRISPR-engineered human natural killer cell lines for research and therapeutic applications.STAR protocols · 2021Article
- Article
- Phenotypic and Functional Characteristics of a Novel Influenza Virus Hemagglutinin-Specific Memory NK Cell.Journal of virology · 2021Article
- The role of NK cells in fighting the virus infection and sepsis.International journal of medical sciences · 2021Review
- Natural Killer Cells as Key Mediators in Type I Diabetes Immunopathology.Frontiers in immunology · 2021Review
- Article
- Natural killer cell responses to emerging viruses of zoonotic origin.Current opinion in virology · 2020Review
- Characterization of the Impact of Daclizumab Beta on Circulating Natural Killer Cells by Mass Cytometry.Frontiers in immunology · 2020Article
- DNAM-1 Activating Receptor and Its Ligands: How Do Viruses Affect the NK Cell-Mediated Immune Surveillance during the Various Phases of Infection?International journal of molecular sciences · 2019Review
- Non-Genetically Improving the Natural Cytotoxicity of Natural Killer (NK) Cells.Frontiers in immunology · 2019Review
- Chronic hepatitis C virus infection irreversibly impacts human natural killer cell repertoire diversity.Nature communications · 2018Article
- Diversification of human NK cells: Lessons from deep profiling.Journal of leukocyte biology · 2018Review
- Redefining Memory: Building the Case for Adaptive NK Cells.Journal of virology · 2017Review
- Natural Killer Cell Diversity in Viral Infection: Why and How Much?Pathogens & immunity · 2016Article
- Characterization of a human anti-tumoral NK cell population expanded after BCG treatment of leukocytes.OncoimmunologyArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Natural killer (NK) cells are a unique lymphocyte lineage with remarkable agility in the rapid destruction of virus-infected cells. They are also the most poorly understood class of lymphocyte. A spectrum of activating and inhibitory receptors at the NK cell surface leads to an unusual and difficult-to-study mechanism of cellular recognition, as well as a very high capacity for diversity at the single-cell level. Here, we review the evidence for the role of NK cells in the earliest stage of human viral infection, and in its prevention. We argue that single-cell diversity is a logical evolutionary adaptation for their position in the immune response and contributes to their ability to kill virus-infected cells. Finally, we look to the future, where emerging single-cell technologies will enable a new generation of rigorous and clinically relevant studies on NK cells accounting for all of their unique and diverse characteristics.
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