Evidence map›Paper›PMID 26973630›Full record

ReviewFrontiers in microbiology2016

Infection Strategies of Intestinal Parasite Pathogens and Host Cell Responses.

Bruno M Di Genova, Renata R Tonelli

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it, 105 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. T cell exhaustion inParasite epidemiology and control · 2026
    Review
  4. Parasitology · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review: Impact of food safety on global trade.Veterinary medicine and science · 2024
    Review
  11. Article
  12. Article
  13. The First Identification ofVeterinary sciences · 2023
    Article
  14. Review
  15. Article
  16. Article
  17. ExploringFrontiers in cellular and infection microbiology · 2023
    Review
  18. Article
  19. In vivo evaluation of anticryptosporidial effects of wheat germ extracts in immunocompromised mice.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Bruno M Di GenovaDepartamento de Microbiologia e Imunologia, Universidade Federal de São Paulo São Paulo, Brazil.
Renata R TonelliDepartamento de Microbiologia e Imunologia, Universidade Federal de São PauloSão Paulo, Brazil; Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Departamento de Ciências Biológicas, Universidade Federal de São PauloDiadema, Brazil.
Instituto de Ciências Farmacêuticas · BRUniversidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Giardia lamblia, Cryptosporidium sp., and Entamoeba histolytica are important pathogenic intestinal parasites and are amongst the leading causes worldwide of diarrheal illness in humans. Diseases caused by these organisms, giardiasis, cryptosporidiosis, and amoebiasis, respectively, are characterized by self-limited diarrhea but can evolve to long-term complications. The cellular and molecular mechanisms underlying the pathogenesis of diarrhea associated with these three pathogens are being unraveled, with knowledge of both the strategies explored by the parasites to establish infection and the methods evolved by hosts to avoid it. Special attention is being given to molecules participating in parasite-host interaction and in the mechanisms implicated in the diseases' pathophysiologic processes. This review focuses on cell mechanisms that are modulated during infection, including gene transcription, cytoskeleton rearrangements, signal transduction pathways, and cell death.

Indexed as

diarrheagastrointestinal tractintestinal epithelial barrierintestinal infectionparasite–host interactionprotozoan parasites

Identifiers

PMID26973630
PMCPMC4776161
OpenAlexW2298987281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.