ReviewFrontiers in psychiatry2016
DTI and Myelin Plasticity in Bipolar Disorder: Integrating Neuroimaging and Neuropathological Findings.
Review in Frontiers in psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.
- The uncinate fasciculus in individuals with and at risk for bipolar disorder: A meta-analysis.Journal of affective disorders · 2022Pooled it
- White Matter Microstructure in Individuals With and At Risk for Bipolar Disorder: Evidence for an Endophenotype From a Voxel-Based Meta-analysis.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2020Pooled it
- A High-Accuracy and Easy-Use Differential Diagnosis Method of Bipolar Disorder Depressive Phase and Major Depressive Disorder Using a Wearable Near-Infrared Spectroscopy.Bipolar disorders · 2026Article
- Translational In Vivo Assays in Behavioral Biology.Annual review of pharmacology and toxicology · 2024Review
- Divergent epigenetic responses to perinatal asphyxia in severe mental disorders.Translational psychiatry · 2024Article
- Microstructural alterations of major thalamic nuclei in the chronic pediatric spinal cord injured population.World neurosurgery: X · 2024Article
- Serum Levels of S100B Protein and Myelin Basic Protein as a Potential Biomarkers of Recurrent Depressive Disorders.Journal of personalized medicine · 2023Article
- Disrupted white matter microstructure correlates with impulsivity in children and adolescents with bipolar disorder.Journal of psychiatric research · 2023Article
- Insights into myelin dysfunction in schizophrenia and bipolar disorder.World journal of psychiatry · 2022Review
- A unified model of the pathophysiology of bipolar disorder.Molecular psychiatry · 2022Review
- Current Insights Into Oligodendrocyte Metabolism and Its Power to Sculpt the Myelin Landscape.Frontiers in cellular neuroscience · 2022Review
- Association of Birth Asphyxia With Regional White Matter Abnormalities Among Patients With Schizophrenia and Bipolar Disorders.JAMA network open · 2021Article
- Differentiating white matter measures that protect against vs. predispose to bipolar disorder and other psychopathology in at-risk youth.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Article
- White matter abnormalities in adults with bipolar disorder type-II and unipolar depression.Scientific reports · 2021Article
- Amide signal intensities may be reduced in the motor cortex and the corticospinal tract of ALS patients.European radiology · 2021Article
- Exploring Signatures of Neurodegeneration in Early-Onset Older-Age Bipolar Disorder and Behavioral Variant Frontotemporal Dementia.Frontiers in neurology · 2021Article
- White Matter Microstructure in Pediatric Bipolar Disorder and Disruptive Mood Dysregulation Disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2020Article
- White matter microstructure in youth with and at risk for bipolar disorder.Bipolar disorders · 2020Article
- State-Independent and -Dependent Structural Connectivity Alterations in Depression.Frontiers in psychiatry · 2020Article
- Neuroinflammation in Bipolar Depression.Frontiers in psychiatry · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bipolar disorder (BD) is a major psychiatric illness with a chronic recurrent course, ranked among the worldwide leading disabling diseases. Its pathophysiology is still not completely understood and findings are still inconclusive, though a great interest on the topic has been constantly raised by magnetic resonance imaging, genetic and neuropathological studies. In recent years, diffusion tensor imaging (DTI) investigations have prompted interest in the key role of white matter (WM) abnormalities in BD. In this report, we summarize and comment recent findings from DTI studies in BD, reporting fractional anisotropy as putative measure of WM integrity, as well as recent data from neuropathological studies focusing on oligodendrocyte involvement in WM alterations in BD. DTI research indicates that BD is most commonly associated with a WM disruption within the fronto-limbic network, which may be accompanied by other WM changes spread throughout temporal and parietal regions. Neuropathological studies, mainly focused on the fronto-limbic network, have repeatedly shown a loss in cortical and subcortical oligodendrocyte cell count, although an increased subcortical oligodendrocyte density has been also documented suggesting a putative role in remyelination processes for oligodendrocytes in BD. According to our review, a greater integration between DTI and morphological findings is needed in order to elucidate processes affecting WM, either glial loss or myelin plasticity, on the basis of a more targeted research in BD.
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