Evidence map›Paper›PMID 26973531›Full record

ReviewFrontiers in pharmacology2016

The Molecular Links of Re-Emerging Therapy: A Review of Evidence of Brahmi (Bacopa monniera).

Deepali Mathur, Kritika Goyal, Veena Koul, Akshay Anand

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
9.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Phyto-pharmacological Potential ofRecent advances in food, nutrition & agriculture · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Depression and Its Phytopharmacotherapy-A Narrative Review.International journal of molecular sciences · 2023
    Review
  15. Journal of clinical and translational research · 2023
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Deepali MathurDepartment of Functional Biology, Faculty of Biological Sciences, University of Valencia Valencia, Spain.
Kritika GoyalNeuroscience Research Lab, Department of Neurology, Post Graduate Institute of Medical Education and Research Chandigarh, India.
Veena KoulCenter for Biomedical Engineering, Indian Institute of Technology New Delhi, India.
Akshay AnandNeuroscience Research Lab, Department of Neurology, Post Graduate Institute of Medical Education and Research Chandigarh, India.
Post Graduate Institute of Medical Education and Research · INIndian Institute of Technology Delhi · INUniversitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The convolution associated with memory is being resolved with advancement in neuroscience. According to the concurrent assumptions, synaptic plasticity forms one of the basis of memory formation, stabilization and strengthening. In Alzheimer's disease (AD), which is generally characterized by memory dysfunction, connections amongst the cells in the brain are attenuated or lost leading to degeneration of neural networks. Numerous attempts have been made to find new therapies for memory dysfunction with increasing attention and investments being laid on herbal drugs. Many herbal plants and extracts have already documented beneficial results when tested for antiamnesic effects. Brahmi (Bacopa monniera) is one such common herbal drug, which is employed for a long time in the Indian and Chinese medical system in order to treat several disorders. Previous research has shown that Brahmi exerts many pharmacological effects including memory boosting capacity in the treatment of Alzheimer's disease and Schizophrenia, exhibiting antiparkinsonian, antistroke, and anticonvulsant potentials. The present review discusses the chemical constituents of Brahmi along with in vitro and in vivo studies based on the pharmacological effects exerted by it. The efficacy of Brahmi in treating various disorders has evoked sufficient research in recent years and now it is a time to launch multiple clinical trials.

Indexed as

anti-convulsantanti-depressantanti-parkinsonBrahmiclinical trialspharmacological effects

Identifiers

PMID26973531
PMCPMC4778428
OpenAlexW2297398483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.