ArticleFrontiers in aging neuroscience2016
The Lateralization of Intrinsic Networks in the Aging Brain Implicates the Effects of Cognitive Training.
Article in Frontiers in aging neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The Effects of Cognitive Training on Brain Network Activity and Connectivity in Aging and Neurodegenerative Diseases: a Systematic Review.Neuropsychology review · 2020Pooled it
- The impact of behavioral interventions on cognitive function in healthy older adults: A systematic review.Ageing research reviews · 2019Pooled it
- State of the Science of Neural Systems in Late-Life Depression: Impact on Clinical Presentation and Treatment Outcome.Journal of the American Geriatrics Society · 2018Pooled it
- Trial
- Cognitive training reorganizes lateralization of fronto-parietal network in vascular cognitive impairment.Brain communications · 2025Article
- Changes of neural coupling between cognitive and motor networks associated with dual-task performance in Parkinson's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024Article
- Article
- The role of the primary sensorimotor system in generalized epilepsy: Evidence from the cerebello-cerebral functional integration.Human brain mapping · 2024Article
- Lateralization of Resting-State Networks in Children: Association with Age, Sex, Handedness, Intelligence Quotient, and Behavior.Brain connectivity · 2022Article
- Effects of multi-domain cognitive training on working memory retrieval in older adults: behavioral and ERP evidence from a Chinese community study.Scientific reports · 2021Article
- Working Memory Training and Cortical Arousal in Healthy Older Adults: A Resting-State EEG Pilot Study.Frontiers in aging neuroscience · 2021Article
- The Neurocognitive Effects ofFrontiers in aging neuroscience · 2021Article
- Older adults benefit from more widespread brain network integration during working memory.NeuroImage · 2020Article
- The effect of cognitive training on the brain's local connectivity organization in healthy older adults.Scientific reports · 2019Article
- Aberrant Interhemispheric Functional Organization in Children with Dyskinetic Cerebral Palsy.BioMed research international · 2019Article
- Effects of Different Cognitive Trainings on Amnestic Mild Cognitive Impairment in the Elderly: A One-Year Longitudinal Functional Magnetic Resonance Imaging (MRI) Study.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- A Randomized Controlled ERP Study on the Effects of Multi-Domain Cognitive Training and Task Difficulty on Task Switching Performance in Older Adults.Frontiers in human neuroscience · 2017Article
- The Impact of Cognitive Training on Cerebral White Matter in Community-Dwelling Elderly: One-Year Prospective Longitudinal Diffusion Tensor Imaging Study.Scientific reports · 2016Article
- Effects of Cognitive Training on Resting-State Functional Connectivity of Default Mode, Salience, and Central Executive Networks.Frontiers in aging neuroscience · 2016Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lateralization of function is an important organization of the human brain. The distribution of intrinsic networks in the resting brain is strongly related to cognitive function, gender and age. In this study, a longitudinal design with 1 year's duration was used to evaluate the cognitive training effects on the lateralization of intrinsic networks among healthy older adults. The subjects were divided into two groups randomly: one with multi-domain cognitive training over 3 months and the other as a wait-list control group. Resting state fMRI data were acquired before training and 1 year after training. We analyzed the functional lateralization in 10 common resting state fMRI networks. We observed statically significant training effects on the lateralization of two important RSNs related to high-level cognition: right- and left- frontoparietal networks (FPNs). The lateralization of the left-FPN was retained especially well in the training group but decreased in the control group. The increased lateralization with aging was observed in the cerebellum network (CereN), in which the lateralization was significantly increased in the control group, although the same change tendency was observed in the training group. These findings indicate that the lateralization of the high-level cognitive intrinsic networks is sensitive to multi-domain cognitive training. This study provides neuroimaging evidence to support the hypothesis that cognitive training should have an advantage in preventing cognitive decline in healthy older adults.
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