Evidence map›Paper›PMID 26973406›Full record

ReviewWorld journal of gastroenterology2016

Outcomes of abdominal surgery in patients with liver cirrhosis.

Juan C Lopez-Delgado, Josep Ballus, Francisco Esteve, Nelson L Betancur-Zambrano, Vicente Corral-Velez, Rafael Mañez, Antoni J Betbese, Joan A Roncal, Casimiro Javierre

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02987712 (Management of Coagulopathy in Cirrhotic Patients Undergoing Invasive Procedures), which is not on this map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02987712 naunknown statusnot on this map

Management of Coagulopathy in Cirrhotic Patients Undergoing Invasive Procedures: a Prospective Trial Comparing Standard Management to Thromboelastography Protocol Based Management

TypeinterventionalSponsorTel-Aviv Sourasky Medical CenterRan2016 to 2018Enrolled120ConditionsLiver Cirrhosis, CoagulopathyArmsThromboelastography based protocol
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Pooled it
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  20. CIRRHOTIC PATIENTS WITH ACUTE KIDNEY INJURY (AKI) HAVE HIGHER MORTALITY AFTER ABDOMINAL HERNIA SURGERY.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Juan C Lopez-DelgadoJuan C Lopez-Delgado, Josep Ballus, Francisco Esteve, Nelson L Betancur-Zambrano, Vicente Corral-Velez, Rafael Mañez, Hospital Universitari de Bellvitge, Intensive Care Department, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Josep BallusJuan C Lopez-Delgado, Josep Ballus, Francisco Esteve, Nelson L Betancur-Zambrano, Vicente Corral-Velez, Rafael Mañez, Hospital Universitari de Bellvitge, Intensive Care Department, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Francisco EsteveJuan C Lopez-Delgado, Josep Ballus, Francisco Esteve, Nelson L Betancur-Zambrano, Vicente Corral-Velez, Rafael Mañez, Hospital Universitari de Bellvitge, Intensive Care Department, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Nelson L Betancur-ZambranoJuan C Lopez-Delgado, Josep Ballus, Francisco Esteve, Nelson L Betancur-Zambrano, Vicente Corral-Velez, Rafael Mañez, Hospital Universitari de Bellvitge, Intensive Care Department, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Vicente Corral-VelezJuan C Lopez-Delgado, Josep Ballus, Francisco Esteve, Nelson L Betancur-Zambrano, Vicente Corral-Velez, Rafael Mañez, Hospital Universitari de Bellvitge, Intensive Care Department, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Rafael MañezJuan C Lopez-Delgado, Josep Ballus, Francisco Esteve, Nelson L Betancur-Zambrano, Vicente Corral-Velez, Rafael Mañez, Hospital Universitari de Bellvitge, Intensive Care Department, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Antoni J BetbeseJuan C Lopez-Delgado, Josep Ballus, Francisco Esteve, Nelson L Betancur-Zambrano, Vicente Corral-Velez, Rafael Mañez, Hospital Universitari de Bellvitge, Intensive Care Department, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Joan A RoncalJuan C Lopez-Delgado, Josep Ballus, Francisco Esteve, Nelson L Betancur-Zambrano, Vicente Corral-Velez, Rafael Mañez, Hospital Universitari de Bellvitge, Intensive Care Department, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Casimiro JavierreJuan C Lopez-Delgado, Josep Ballus, Francisco Esteve, Nelson L Betancur-Zambrano, Vicente Corral-Velez, Rafael Mañez, Hospital Universitari de Bellvitge, Intensive Care Department, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Hospital de Sant Pau · ESInstitut d'Investigació Biomédica de Bellvitge · ESAjuntament de L’Hospitalet · ESUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients suffering from liver cirrhosis (LC) frequently require non-hepatic abdominal surgery, even before liver transplantation. LC is an important risk factor itself for surgery, due to the higher than average associated morbidity and mortality. This high surgical risk occurs because of the pathophysiology of liver disease itself and to the presence of contributing factors, such as coagulopathy, poor nutritional status, adaptive immune dysfunction, cirrhotic cardiomyopathy, and renal and pulmonary dysfunction, which all lead to poor outcomes. Careful evaluation of these factors and the degree of liver disease can help to reduce the development of complications both during and after abdominal surgery. In the emergency setting, with the presence of decompensated LC, alcoholic hepatitis, severe/advanced LC, and significant extrahepatic organ dysfunction conservative management is preferred. A multidisciplinary, individualized, and specialized approach can improve outcomes; preoperative optimization after risk stratification and careful management are mandatory before surgery. Laparoscopic techniques can also improve outcomes. We review the impact of LC on surgical outcome in non-hepatic abdominal surgeries required in this cirrhotic population before, during, and after surgery.

Indexed as

AbdomenHealth StatusHumansLaparotomyLiver CirrhosisPerioperative CarePostoperative ComplicationsRisk AssessmentRisk FactorsTreatment OutcomeAbdominal surgeryAdaptive immune dysfunctionCirrhotic cardiomyopathyCoagulopathyLiver cirrhosisNutritional statusOutcomes

Identifiers

PMID26973406
PMCPMC4777990
OpenAlexW2314125820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.