Evidence map›Paper›PMID 26972900›Full record

ArticleThe Laryngoscope2016

Practice variations in voice treatment selection following vocal fold mucosal resection.

Jaime E Moore, Paul J Rathouz, Jeffrey A Havlena, Qianqian Zhao, Seth H Dailey, Maureen A Smith, Caprice C Greenberg, Nathan V Welham

Open access · greenAbstract read
In one paragraph

Article in The Laryngoscope, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Genetic polymorphisms and protein levels in vocal fold leukoplakia: a systematic review.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022
    Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jaime E MooreDivision of Otolaryngology, Department of Surgery , University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
Paul J RathouzDepartment of Biostatistics and Medical Informatics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
Jeffrey A HavlenaDivision of General Surgery, Department of Surgery , University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
Qianqian ZhaoDepartment of Biostatistics and Medical Informatics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
Seth H DaileyDivision of Otolaryngology, Department of Surgery , University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
Maureen A SmithDepartment of Population Health Sciences, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
Caprice C GreenbergDivision of General Surgery, Department of Surgery , University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.
Nathan V WelhamDivision of Otolaryngology, Department of Surgery , University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, U.S.A.. welham@surgery.wisc.edu.
University of Wisconsin–Madison · USUniversity of Wisconsin Health · US

Funding

Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
PHONOSURGICAL OPTIMIZATION CRITERIA FOR SULCUS VOCALISR01DC004428 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI Nathan Welham · 2000 to 2026
$8.7M
Regeneration of Multi-Layered Vocal Fold MucosaR01DC010777 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI WELHAM, NATHAN · 2010 to 2020
$5.3M
NCATS NIH HHS UL1 TR000427NIDCD NIH HHS R01 DC004428NIDCD NIH HHS R01 DC010777
6 · The paper itself

Abstract

objectives/hypothesisTo characterize initial voice treatment selection following vocal fold mucosal resection in a Medicare population. STUDY

designRetrospective analysis of a large, nationally representative Medicare claims database.

methodsPatients with > 12 months of continuous Medicare coverage who underwent a leukoplakia- or cancer-related vocal fold mucosal resection (index) procedure during calendar years 2004 to 2009 were studied. The primary outcome of interest was receipt of initial voice treatment (thyroplasty, vocal fold injection, or speech therapy) following the index procedure. We evaluated the cumulative incidence of each postindex treatment type, treating the other treatment types as competing risks, and further evaluated postindex treatment utilization using the proportional hazards model for the subdistribution of a competing risk. Patient age, sex, and Medicaid eligibility were used as predictors.

resultsA total of 2,041 patients underwent 2,427 index procedures during the study period. In 14% of cases, an initial voice treatment event was identified. Women were significantly less likely to receive surgical or behavioral treatment compared to men. From age 65 to 75 years, the likelihood of undergoing surgical treatment increased significantly with each 5-year age increase; after age 75 years, the likelihood of undergoing either surgical or behavioral treatment decreased significantly every 5 years. Patients with low socioeconomic status were significantly less likely to undergo speech therapy.

conclusionThe majority of Medicare patients do not undergo voice treatment following vocal fold mucosal resection. Further, the treatments analyzed here appear disproportionally utilized based on patient sex, age, and socioeconomic status. Additional research is needed to determine whether these observations reflect clinically explainable differences or disparities in care. LEVEL OF EVIDENCE: 2c. Laryngoscope, 126:2505-2512, 2016.

Indexed as

Patient SelectionAgedAged, 80 and overAge FactorsDatabases, FactualFemaleHumansLaryngeal MucosaLaryngeal NeoplasmsLaryngoscopyLeukoplakiaLikelihood FunctionsMaleMedicarePostoperative ComplicationsPractice Patterns, Physicians'DysphoniaMedicarepractice patternsspeech therapythyroplastyvocal fold injectionvoice therapy

Identifiers

PMID26972900
PMCPMC5018919
OpenAlexW2296450186

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.