ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2016
Predictors for surgical complications of en bloc resections in the spine: review of 220 cases treated by the same team.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.
- Factors associated with spinal fixation mechanical failure after tumor resection: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2022Pooled it
- Use of patient-specific 3D reconstruction models for en bloc resection of primary thoracic vertebral sarcomas without formal spondylectomy: illustrative cases.Journal of neurosurgery. Case lessons · 2026Article
- Novel application of FiberWire for intervertebral disc transection in en bloc spondylectomy: a case report.Journal of spine surgery (Hong Kong) · 2026Article
- Surgical technique and outcomes for tumors simultaneously involving the thoracic vertebrae and posterior chest wall.BMC cancer · 2026Article
- Survival outcomes and prognostic factors of breast cancer spinal metastases: a retrospective study.Discover oncology · 2025Article
- Comparation of tumor-free margin or intralesional spondylectomy for chondrosarcoma in mobile spine: a retrospective study of surgery management, complications and prognosis.Journal of orthopaedic surgery and research · 2025Article
- En bloc resection for primary spinal tumors with huge intrathoracic involvement: a surgical intervention for neurological decompression and oncological control.Frontiers in neurology · 2025Article
- Safety and risk analysis of total resection surgery for thoracic and lumbar spinal tumors: a decadal analysis of 103 cases.World journal of surgical oncology · 2024Article
- Spinal chordoma and chondrosarcoma treatment experiences - a 20-year retrospective study from databases of two medical centers.Scientific reports · 2024Article
- En Bloc Total Vertebrectomy of the Thoracic and Lumbar Spine.Journal of clinical medicine · 2024Article
- Advances in the multidisciplinary surgical approach to primary spinal sarcomas: insights from a retrospective case series on outcomes and survival.Acta neurochirurgica · 2024Article
- Sagittal en bloc resection of thoracolumbar tumours: a report of thirty one cases.International orthopaedics · 2024Article
- Two-step osteotomy/discectomy through cannulated screw (TOCS) technique for en bloc resection of spine tumor: surgical technique and preliminary results.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- Complications and local recurrence of chondrosarcoma and chordoma treated by total tumor resection in thoracic and lumbar spine.BMC musculoskeletal disorders · 2024Article
- Nomogram for predicting postoperative pulmonary complications in spinal tumor patients.BMC anesthesiology · 2024Article
- Health-related quality of life in patients treated with en bloc resection for primary tumors of the spine.Frontiers in oncology · 2024Article
- Surgical Strategy for Recurrent Giant Cell Tumor in the Thoracolumbar Spine.Orthopaedic surgery · 2024Article
- Surgical outcomes and risk factors for surgical complications after en bloc resection following reconstruction with 3D-printed artificial vertebral body for thoracolumbar tumors.World journal of surgical oncology · 2023Article
- Mini-open compared with the trans-tubular approach in patients with spinal metastases underwent decompression surgery---a retrospective cohort study.BMC cancer · 2023Article
- The Impact of Frailty on Postoperative Complications in Total En Bloc Spondylectomy for Spinal Tumors.Journal of clinical medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIdentify risk factors, enabling reduction of the rate of complications and improve outcome in en bloc resection surgeries.
methodsA retrospective study of prospective collected data of 1681 patients affected by spine tumors treated from 1990 to 2015 by the same team.
resultsA total of 220 en bloc resections that were performed on 216 patients during that period. Most of the tumors were primary-165 cases (43 benign and 122 malignant), metastases occurred in 55 cases. Median FU was 45 months (0-371). 153 complications were observed in 100 patients (46.2 %). 64 (30 %) suffered one complication, while the rest had two or more. There were 105 major and 48 minor complications. Seven patients (4.6 %) died as a result of complications. The combined approach, neoadjuvant chemotherapy and neoadjuvant radiotherapy were statistically significant independent risk factors for complications occurrence. 33 patients (15.2 %) suffered from local recurrence. Reoperations were mostly due to tumor recurrences, but also to hardware failures, wound dehiscence, hematomas and aortic dissection.
conclusionThe rate of complication is higher in multisegmental resections and when double combined approach is performed. Reoperations display greater morbidity owing to dissection through scar/fibrosis from previous operations and possibly from RT. Careful treatment planning and, in the event of uncertainty, referral to a specialty center must be stressed. The high risk of complications should not discourage surgeons from performing en bloc resection when needed. Most of the patients who sustain complications benefit from the better local control resulting from en bloc resection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.