Evidence map›Paper›PMID 26972102›Full record

ArticleClinical journal of gastroenterology2016

Humoral hypercalcemia due to gastric carcinoma secreting parathyroid hormone-related protein during chemotherapy: a case report.

Chikara Iino, Tadashi Shimoyama, Yui Akemoto, Takasato Igarashi, Tomoyuki Aihara, Kentaro Ishii, Juichi Sakamoto, Hiroshi Tono, Shinsaku Fukuda

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Clinical journal of gastroenterology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chikara IinoDepartment of Internal Medicine, Hirosaki Municipal Hospital, Hirosaki, Japan. chikaran0601@yahoo.co.jp.
Tadashi ShimoyamaDepartment of Gastroenterology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Yui AkemotoDepartment of Internal Medicine, Hirosaki Municipal Hospital, Hirosaki, Japan.
Takasato IgarashiDepartment of Internal Medicine, Hirosaki Municipal Hospital, Hirosaki, Japan.
Tomoyuki AiharaDepartment of Internal Medicine, Hirosaki Municipal Hospital, Hirosaki, Japan.
Kentaro IshiiDepartment of Internal Medicine, Hirosaki Municipal Hospital, Hirosaki, Japan.
Juichi SakamotoDepartment of Internal Medicine, Hirosaki Municipal Hospital, Hirosaki, Japan.
Hiroshi TonoDepartment of Internal Medicine, Hirosaki Municipal Hospital, Hirosaki, Japan.
Shinsaku FukudaDepartment of Gastroenterology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan.
Ogaki Municipal Hospital · JPHirosaki University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Humoral hypercalcemia due to a gastric carcinoma-secreting parathyroid hormone-related protein (PTHrP) is a rare disease associated with poor prognosis. A 61-year-old male with gastric cancer who had been receiving chemotherapy showed serum hypercalcemia and an elevated level of serum PTHrP with a suppressed intact parathyroid hormone level. Computed tomography revealed stable disease 4 weeks prior, and the laboratory examination revealed no adverse effects 2 weeks prior. The biopsy at the time of diagnosis was immunohistochemically positive for PTHrP later. Despite intensive care, the patient died of multiorgan failure on the 14th day after admission. In case of undifferentiated gastric cancer, the possibility of humoral hypercalcemia of malignancy caused by gastric cancer should be considered even when the patient is receiving chemotherapy.

Indexed as

AdenocarcinomaCarcinoma, Signet Ring CellFatal OutcomeHumansHypercalcemiaMaleMiddle AgedParathyroid Hormone-Related ProteinStomach NeoplasmsParathyroid Hormone-Related ProteinGastric cancerHumoral hypercalcemia of malignancy (HHM)Parathyroid hormone-related protein (PTHrP)

Identifiers

PMID26972102
OpenAlexW2304318834

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.