ArticleCell chemical biology2016
"Death is my Heir"--Ferroptosis Connects Cancer Pharmacogenomics and Ischemia-Reperfusion Injury.
Article in Cell chemical biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- In defence of ferroptosis.Signal transduction and targeted therapy · 2025Review
- The TF/Nrf2/GSTP1 pathway is involved in stress-induced hepatocellular injury through ferroptosis.Journal of cellular and molecular medicine · 2024Article
- A Deep Insight into Ferroptosis in Renal Disease: Facts and Perspectives.Kidney diseases (Basel, Switzerland) · 2024Review
- Ferroptosis: a novel mechanism of cell death in ophthalmic conditions.Frontiers in immunology · 2024Review
- Unveiling ferroptosis: a new frontier in skin disease research.Frontiers in immunology · 2024Review
- PPARα alleviates iron overload-induced ferroptosis in mouse liver.EMBO reports · 2022Article
- Types of necroinflammation, the effect of cell death modalities on sterile inflammation.Cell death & disease · 2022Review
- Mechanism of Ferroptosis and Its Relationships with Other Types of Programmed Cell Death: Insights for Potential Therapeutic Benefits in Traumatic Brain Injury.Oxidative medicine and cellular longevity · 2022Review
- Ferroptosis Meets Cell-Cell Contacts.Cells · 2021Review
- The role of regulated necrosis in endocrine diseases.Nature reviews. Endocrinology · 2021Review
- Ferroptosis: a cell death connecting oxidative stress, inflammation and cardiovascular diseases.Cell death discovery · 2021Review
- The Multifaceted Regulation of Mitochondria in Ferroptosis.Life (Basel, Switzerland) · 2021Review
- Targeting Ferroptosis for Lung Diseases: Exploring Novel Strategies in Ferroptosis-Associated Mechanisms.Oxidative medicine and cellular longevity · 2021Review
- Targeting ferroptosis in breast cancer.Biomarker research · 2020Review
- Ferroptosis: regulated cell death.Arhiv za higijenu rada i toksikologiju · 2020Review
- Ferroptosis in Cancer Cell Biology.Cancers · 2020Review
- Roles of TRAFs in Ischemia-Reperfusion Injury.Frontiers in cell and developmental biology · 2020Review
- Liproxstatin-1 Protects Hair Cell-Like HEI-OC1 Cells and Cochlear Hair Cells against Neomycin Ototoxicity.Oxidative medicine and cellular longevity · 2020Article
- Impact of Prolonged Mechanical Ventilation on Ferroptosis in Renal Ischemia/Reperfusion Injury in Rats.BioMed research international · 2020Article
- The Potential Role of Ferroptosis in Neonatal Brain Injury.Frontiers in neuroscience · 2019Review
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although they are key to precision medicine, pharmacokinetics and pharmacogenomics are currently plagued with inconsistent results. In this issue of Cell Chemical Biology, Shimada et al. (2016) use cell line selectivity and appropriate filters to improve the consistency and to identify biomarkers for the selectivity of lethal compounds. These insights may be useful for our understanding of how necrosis and ischemic injury are regulated.
Indexed as
Identifiers
26971867What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.