Evidence map›Paper›PMID 26971498›Full record

ArticleJournal of bioenergetics and biomembranes2017

Divalent cation chelators citrate and EDTA unmask an intrinsic uncoupling pathway in isolated mitochondria.

Anatoly A Starkov, Christos Chinopoulos, Natalia N Starkova, Csaba Konrad, Gergely Kiss, Anna Stepanova, Vasily N Popov

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bioenergetics and biomembranes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Editorial note.Journal of bioenergetics and biomembranes · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 4 countries.

Anatoly A StarkovThe Feil Family Brain and Mind Research Institute, Weill Cornell Medical College, 407 East 61st Street, New York, NY, 10065, USA. ans2024@med.cornell.edu.ORCID http://orcid.org/0000-0002-1334-4828
Christos ChinopoulosDepartment of Medical Biochemistry, Semmelweis University, Budapest, Hungary.
Natalia N StarkovaDepartment of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Csaba KonradDepartment of Medical Biochemistry, Semmelweis University, Budapest, Hungary.
Gergely KissDepartment of Medical Biochemistry, Semmelweis University, Budapest, Hungary.
Anna StepanovaSchool of Biological Sciences, Medical Biology Centre, Queens University Belfast, Belfast, UK.
Vasily N PopovVoronezh State University, Voronezh, Russia.
Semmelweis University · HUCornell University · USIcahn School of Medicine at Mount Sinai · USQueen's University Belfast · GBVoronezh State University · RU

Funding

TRANSCRIPTIONAL RESPONSES TO MITOCHONDRIAL DYSFUNCTIONP01AG014930 · NIA · WINIFRED MASTERSON BURKE MED RES INST · PI GIBSON, GARY E · 1999 to 2020
$30.7M
NIA NIH HHS P01 AG014930
6 · The paper itself

Abstract

We demonstrate a suppression of ROS production and uncoupling of mitochondria by exogenous citrate in Mg

Indexed as

AnimalsBiological TransportBrainCations, DivalentCitric AcidEdetic AcidHumansHydrogen PeroxideIon ChannelsMagnesium ChlorideMelanomaMiceMitochondriaMitochondrial MembranesRatsReactive Oxygen SpeciesCations, DivalentCitric AcidEdetic AcidHydrogen PeroxideIon ChannelsMagnesium ChlorideReactive Oxygen SpeciesInner membraneMembrane potentialProton channelReactive oxygen speciesUncoupling

Identifiers

PMID26971498
PMCPMC5023464
OpenAlexW2300895276

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.