Evidence map›Paper›PMID 26971141›Full record

ArticleBMC surgery2016

Prognosis and postoperative genital function of function-preservative surgery of pelvic autonomic nerve preservation for male rectal cancer patients.

Zhihua Liu, Meijin Huang, Liang Kang, Lei Wang, Ping Lan, Ji Cui, Jianping Wang

Open access · goldAbstract read
In one paragraph

Article in BMC surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. The erectile and ejaculatory implications of the surgical management of rectal cancer.International journal of urology : official journal of the Japanese Urological Association · 2023
    Review
  3. Article
  4. Male Fertility Preservation.Current urology reports · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhihua LiuGastrointestinal Institute of Sun Yat-Sen University, Department of Colorectal Surgery, the Sixth Affiliated Hospital of Sun Yat-Sen University (Guangdong Gastrointestinal Hospital), 26 Yuancun Erheng Road, Guangzhou, Guangdong, 510655, People's Republic of China.
Meijin HuangGastrointestinal Institute of Sun Yat-Sen University, Department of Colorectal Surgery, the Sixth Affiliated Hospital of Sun Yat-Sen University (Guangdong Gastrointestinal Hospital), 26 Yuancun Erheng Road, Guangzhou, Guangdong, 510655, People's Republic of China.
Liang KangGastrointestinal Institute of Sun Yat-Sen University, Department of Colorectal Surgery, the Sixth Affiliated Hospital of Sun Yat-Sen University (Guangdong Gastrointestinal Hospital), 26 Yuancun Erheng Road, Guangzhou, Guangdong, 510655, People's Republic of China.
Lei WangGastrointestinal Institute of Sun Yat-Sen University, Department of Colorectal Surgery, the Sixth Affiliated Hospital of Sun Yat-Sen University (Guangdong Gastrointestinal Hospital), 26 Yuancun Erheng Road, Guangzhou, Guangdong, 510655, People's Republic of China.
Ping LanGastrointestinal Institute of Sun Yat-Sen University, Department of Colorectal Surgery, the Sixth Affiliated Hospital of Sun Yat-Sen University (Guangdong Gastrointestinal Hospital), 26 Yuancun Erheng Road, Guangzhou, Guangdong, 510655, People's Republic of China.
Ji CuiDepartment of Gastrointestinal Surgery, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.
Jianping WangGastrointestinal Institute of Sun Yat-Sen University, Department of Colorectal Surgery, the Sixth Affiliated Hospital of Sun Yat-Sen University (Guangdong Gastrointestinal Hospital), 26 Yuancun Erheng Road, Guangzhou, Guangdong, 510655, People's Republic of China. j-p-wang@hotmail.com.
Sun Yat-sen University · CNSixth Affiliated Hospital of Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo retrospectively evaluate postoperative genital function, local recurrence rate and survival rate after total mesorectal excision (TME) combined with or without pelvic autonomic nerve preservation (PANP) in male patients with rectal cancer.

methodsA total of 953 male patients with rectal cancer after TME (518 patients received TME combined with PANP [PANP group] and 434patients received TME alone [TME group]) were included. Assessments of postoperative genital function, local recurrence rate, and 5 year survival rate were collected.

resultsRate of erection dysfunction in PANP group (41.9%) was significantly lower than that in TME group (76.7%, P < 0.05). Rate of ejaculation dysfunction in PANP group (42.5%) was also significantly lower than that in TME group (67.3%, P < 0.05). Local recurrence rate (P = 0.66) and survival rate (P = 0.26) did not differ between the two groups. For patients with preoperative obstruction, local recurrence rate was significantly higher (P = 0.01) and survival rate significantly lower (P = 0.03) in PANP group.

conclusionsPANP surgery has significant advantage with respect to preservation of genital function and should be recommended as surgical treatment for rectal cancer patients. However, PANP surgery should be considered with caution in patients with preoperative obstruction in view of the poorer long-term outcomes in these patients.

Indexed as

Postoperative ComplicationsAdultAgedAutonomic PathwaysErectile DysfunctionHumansMaleMiddle AgedNeoplasm Recurrence, LocalPelvisPrognosisRectal NeoplasmsRetrospective StudiesSurvival RateGenital functionPelvic autonomic nerve preservationRectal cancerSurvival rateTotal mesorectal excision

Identifiers

PMID26971141
PMCPMC4789285
OpenAlexW2293540948

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.