Evidence map›Paper›PMID 26970912›Full record

SynthesisEuropean urology2016

Enhanced Recovery after Urological Surgery: A Contemporary Systematic Review of Outcomes, Key Elements, and Research Needs.

Raed A Azhar, Bernard Bochner, James Catto, Alvin C Goh, John Kelly, Hiten D Patel, Raj S Pruthi, George N Thalmann, Mihir Desai

3 registry-linked trialsOpen access · greenAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in European urology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 111 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
111citing papers in PubMed, 12 pooled it
33.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03960697 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Effects of Walking Out From Operating Room on Postoperative Recovery of Patients Undergoing Laparoscopic Total or Partial Nephrectomy

TypeinterventionalSponsorSixth Affiliated Hospital, Sun Yat-sen UniversityRan2019 to 2023Enrolled182ConditionsLaparoscopic Nephrectomy, Enhanced Recovery After SurgeryArmswalk out from operating room
NCT04576533 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Effects of Walking Out From Operating Room on Postoperative Recovery of Patients Undergoing Laparoscopic Colorectal Surgery

TypeinterventionalSponsorSixth Affiliated Hospital, Sun Yat-sen UniversityRan2020 to 2025Enrolled300ConditionsEnhanced Recovery After SurgeryArmswalk out from operating room
NCT05437939 active not recruitingnot on this mapstarted 2022, after this paper: background citation

Identifying Opportunities for Prevention of Adverse Outcomes Following Female Genital

TypeobservationalSponsorUniversity of California, San FranciscoRan2022 to 2026Enrolled802ConditionsFemale Genital Fistula, Incontinence
3 · Its place in the literature

Who cites it

111 citing papers in PubMed, 12 syntheses or guidelines pooled it, 296 citations in OpenAlex.

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  7. [Enhanced recovery after surgery-Does the ERAS concept keep its promises].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021
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51 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 4 countries.

Raed A AzharUrology Department, King Abdulaziz University, Jeddah, Saudi Arabia; USC Institute of Urology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address: raazhar@kau.edu.sa.
Bernard BochnerUrology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York City, NY, USA.
James CattoAcademic Units of Urology and Molecular Oncology, University of Sheffield, Sheffield, South Yorkshire, UK.
Alvin C GohDepartment of Urology, Houston Methodist Hospital, Houston, TX, USA.
John KellyDivision of Surgery and Interventional Science, UCL Medical School, University College London, London, UK.
Hiten D PatelJames Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
Raj S PruthiDivision of Urologic Surgery, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
George N ThalmannDepartment of Urology, University Hospital Inselspital, Bern, Switzerland.
Mihir DesaiUSC Institute of Urology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Johns Hopkins University · USKing Abdulaziz University · SAMemorial Sloan Kettering Cancer Center · USMethodist Hospital · USUniversity College London · GBUniversity Hospital of Bern · CHUniversity of North Carolina at Chapel Hill · USUniversity of Sheffield · GBUniversity of Southern California · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

contextEnhanced Recovery after Surgery (ERAS) programs are multimodal care pathways that aim to decrease intra-operative blood loss, decrease postoperative complications, and reduce recovery times.

objectiveTo overview the use and key elements of ERAS pathways, and define needs for future clinical trials. EVIDENCE ACQUISITION: A comprehensive systematic MEDLINE search was performed for English language reports published before May 2015 using the terms "postoperative period," "postoperative care," "enhanced recovery after surgery," "enhanced recovery," "accelerated recovery," "fast track recovery," "recovery program," "recovery pathway", "ERAS," and "urology" or "cystectomy" or "urologic surgery." EVIDENCE SYNTHESIS: We identified 18 eligible articles. Patient counseling, physical conditioning, avoiding excessive alcohol and smoking, and good nutrition appeared to protect against postoperative complications. Fasting from solid food for only 6h and perioperative liquid-carbohydrate loading up to 2h prior to surgery appeared to be safe and reduced recovery times. Restricted, balanced, and goal-directed fluid replacement is effective when individualized, depending on patient morbidity and surgical procedure. Decreased intraoperative blood loss may be achieved by several measures. Deep vein thrombosis prophylaxis, antibiotic prophylaxis, and thermoregulation were found to help reduce postsurgical complications, as was a multimodal approach to postoperative nausea, vomiting, and analgesia. Chewing gum, prokinetic agents, oral laxatives, and an early resumption to normal diet appear to aid faster return to normal bowel function. Further studies should compare anesthetic protocols, refine analgesia, and evaluate the importance of robot-assisted surgery and the need/timing for drains and catheters.

conclusionsERAS regimens are multidisciplinary, multimodal pathways that optimize postoperative recovery. PATIENT SUMMARY: This review provides an overview of the use and key elements of Enhanced Recovery after Surgery programs, which are multimodal, multidisciplinary care pathways that aim to optimize postoperative recovery. Additional conclusions include identifying effective procedures within Enhanced Recovery after Surgery programs and defining needs for future clinical trials.

Indexed as

Urologic Surgical ProceduresDietEarly AmbulationPerioperative CarePostoperative ComplicationsRecovery of FunctionSmoking CessationTime FactorsEnhanced recovery after surgeryERASPerioperative care

Identifiers

PMID26970912
PMCPMC5514421
OpenAlexW2294945063

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.