Evidence map›Paper›PMID 26970638›Full record

ReviewCurrent topics in developmental biology2016

Tales of Tails (and Trunks): Forming the Posterior Body in Vertebrate Embryos.

David Kimelman

Abstract readReview
In one paragraph

Review in Current topics in developmental biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
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  8. Induction andbioRxiv : the preprint server for biology · 2024
    Article
  9. Article
  10. Functional analysis of a first hindlimb positioning enhancer viaFrontiers in cell and developmental biology · 2024
    Article
  11. Article
  12. Article
  13. Hinge point emergence in mammalian spinal neurulation.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

David KimelmanDepartment of Biochemistry, University of Washington, Seattle, Washington, USA. Electronic address: kimelman@uw.edu.

Funding

Regulation of Mesodermal Progenitors in Transgenic ZebrafishR01GM079203 · NIGMS · UNIVERSITY OF WASHINGTON · PI KIMELMAN, DAVID · 2008 to 2020
$4.0M
NIGMS NIH HHS GM079203NIGMS NIH HHS R01 GM079203
6 · The paper itself

Abstract

A major question in developmental biology is how the early embryonic axes are established. Recent studies using different model organisms and mammalian in vitro systems have revealed the surprising result that most of the early posterior embryonic body forms from a Wnt-regulated bipotential neuromesodermal progenitor population that escapes early germ layer patterning. Part of the regulatory network that drives the maintenance and differentiation of these progenitors has recently been determined, but much remains to be discovered. This review discusses some of the common features present in all vertebrates, as well as unique aspects that different species utilize to establish their anterior-posterior (A-P) axis.

Indexed as

Body PatterningCell DifferentiationAnimalsGene Expression Regulation, DevelopmentalSignal TransductionVertebratesWnt ProteinsWnt ProteinsNeuromesodermal cellsPosterior bodyProgenitor cellsTailVertebrate developmentWnt signaling

Identifiers

PMID26970638
PMCPMC4883064

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.