Evidence map›Paper›PMID 26970626›Full record

ReviewCurrent topics in developmental biology2016

Connectomics, the Final Frontier.

Scott W Emmons

Abstract readReview
In one paragraph

Review in Current topics in developmental biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Terror in the dirt: Sensory determinants of host seeking in soil-transmitted mammalian-parasitic nematodes.International journal for parasitology. Drugs and drug resistance · 2018
    Review
  5. Article
  6. Olfactory circuits and behaviors of nematodes.Current opinion in neurobiology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Scott W EmmonsDepartment of Genetics, Albert Einstein College of Medicine, Bronx, New York, USA; Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York, USA. Electronic address: scott.emmons@einstein.yu.edu.

Funding

Genetic Analysis of Nematode BehaviorR01GM066897 · NIGMS · YESHIVA UNIVERSITY · PI EMMONS, SCOTT W · 2003 to 2013
$2.2M
GENETIC ANALYSIS OF MORPHOGENESIS IN A NEMATODER01GM039353 · NIGMS · YESHIVA UNIVERSITY · PI EMMONS, SCOTT W · 1988 to 2005
$1.9M
NIGMS NIH HHS R01 GM039353NIGMS NIH HHS R01 GM066897
6 · The paper itself

Abstract

How the synaptic connections in the nervous system are genetically encoded and formed during development remains an unsolved problem. The known connectivity of the nervous system of the nematode C. elegans provides an opportunity to search for the genes involved. The circuits for male mating behavior form a complex neural network that would seem to require a large family of molecular cell labels for pre- and postsynaptic cell recognition. It is suggested that a combinatorial code of neural cell adhesion proteins specifying the network of connections may be discovered by comparing the expression patterns of candidate genes with the pattern of connections.

Indexed as

Nervous SystemAnimalsCaenorhabditis elegansCell CommunicationConnectomeGene Expression Regulation, DevelopmentalMaleNerve NetNerve Tissue ProteinsSexual Behavior, AnimalSynapsesNerve Tissue ProteinsC. elegansCombinatorial codeNervous systemNervous system developmentNeural cell adhesion proteinNeural networkSynapseSynaptic connectivity

Identifiers

PMID26970626
PMCPMC5693222

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.