SynthesisSurvey of ophthalmology
Anti-tubercular therapy for intraocular tuberculosis: A systematic review and meta-analysis.
Synthesis in Survey of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06613919 (Prospective Randomised Trial for 6-Months Versus 9-Months Anti-TB Therapy for Tubercular Posterior Uveitis), which is not on this map. Cited by 43 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective Randomised Trial for 6-Months Versus 9-Months Anti-TB Therapy for Tubercular Posterior Uveitis
Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systemic review of the utility of antituberculosis therapy for presumed tuberculous uveitis.BMC infectious diseases · 2025Pooled it
- Incidental Papilledema Revealing Neurotuberculosis: A Case Report of a Diagnostic Challenge.Diagnostics (Basel, Switzerland) · 2026Article
- Ocular TB as the only manifestation of TB: diagnostic uncertainty and treatment thresholds.International ophthalmology · 2026Review
- Disseminated Tuberculosis With Ocular Involvement After 12 Years of Anti-TNF-Case reports in ophthalmological medicine · 2026Article
- Design and synthesis of natural antibacterial derivatives for ocular tuberculosis: a comprehensive review.Frontiers in pharmacology · 2025Review
- Presumed Tubercular Multifocal Choroiditis.Journal of ophthalmic & vision research · 2024Article
- Ocular tuberculosis associated with Epstein-Barr virus myelitis: A case report.Infectious medicine · 2024Article
- Ocular Tuberculosis, Anti-Tuberculosis Prophylaxis, and Diseases Confused with Ocular Tuberculosis: Brief Report.Journal of clinical practice and research · 2024Article
- How far should I manage acute optic neuritis as an ophthalmologist? A United Kingdom perspective.Eye (London, England) · 2024Review
- Characteristics and outcomes of the duration of treatment with adjunctive corticosteroids in intraocular tuberculosis.Journal of clinical tuberculosis and other mycobacterial diseases · 2024Article
- Article
- A case of solitary choroidal tuberculoma with highly positive tuberculin skin test and negative interferon gamma release assays.International journal of ophthalmology · 2024Article
- Case Report: Ocular Tissue Diagnosis of Previously Undiagnosed, Extensively Drug-Resistant Pulmonary Tuberculosis.The American journal of tropical medicine and hygiene · 2023Article
- Correlation of angiogenic growth factors and inflammatory cytokines with the clinical phenotype of ocular tuberculosis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Anti-tubercular therapy alone for treatment of isolated tubercular retinal vasculitis.Eye (London, England) · 2022Observational
- Types of Fundus Involvement in Intraocular Tuberculosis.Turkish thoracic journal · 2022Article
- Could different aqueous humor and plasma cytokine profiles help differentiate between ocular sarcoidosis and ocular tuberculosis?Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022Article
- Tuberculosis of the eye, case series study.Journal of medicine and life · 2022Article
- Clinical Manifestations and Outcomes of Tubercular Uveitis in Taiwan-A Ten-Year Multicenter Retrospective Study.Medicina (Kaunas, Lithuania) · 2022Article
- BTS clinical statement for the diagnosis and management of ocular tuberculosis.BMJ open respiratory research · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Intraocular tuberculosis remains a diagnostic and management conundrum for both ophthalmologists and pulmonologists. We analyze the efficacy and safety of anti-tubercular therapy (ATT) in patients with intraocular tuberculosis and factors associated with favorable outcome. Twenty-eight studies are included in this review, with a total of 1,917 patients. Nonrecurrence of inflammation was observed in pooled estimate of 84% of ATT-treated patients (95% CI 79-89). There was minimal difference in the outcome between patients treated with ATT alone (85% successful outcome; 95% CI 25-100) and those with concomitant systemic corticosteroid (82%; 95% CI 73-90). The use of ATT may be of benefit to patients with suspected intraocular tuberculosis; however, this conclusion is limited by the lack of control group analysis and standardized recruitment and treatment protocols. We propose further prospective studies to better establish the efficacy of ATT and ascertain the factors associated with favorable treatment outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.