ReviewHuman brain mapping2016
Cortical chemoarchitecture shapes macroscale effective functional connectivity patterns in macaque cerebral cortex.
Review in Human brain mapping, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed.
- Revealing excitation-inhibition imbalance in Alzheimer's disease using multiscale neural model inversion of resting-state functional MRI.Communications medicine · 2025Article
- Differences in the amplitude of dynamic low-frequency fluctuations in primary angle-closure glaucoma are associated with gene-molecular multi-omics.Frontiers in medicine · 2025Article
- Multilayer network analysis across cortical depths in 7-T resting-state fMRI.Network neuroscience (Cambridge, Mass.) · 2025Article
- Multilayer Network Analysis across Cortical Depths in Resting-State 7T fMRI.bioRxiv : the preprint server for biology · 2024Article
- Multiscale network neuroscience in neuro-oncology: How tumors, brain networks, and behavior connect across scales.Neuro-oncology practice · 2023Review
- Resting state fMRI connectivity is sensitive to laminar connectional architecture in the human brain.Brain informatics · 2022Article
- Constructing the rodent stereotaxic brain atlas: a survey.Science China. Life sciences · 2022Review
- The natural axis of transmitter receptor distribution in the human cerebral cortex.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Analyzing synchronized clusters in neuron networks.Scientific reports · 2020Article
- Microstructure-Informed Connectomics: Enriching Large-Scale Descriptions of Healthy and Diseased Brains.Brain connectivity · 2019Review
- Connection strength of the macaque connectome augments topological and functional network attributes.Network neuroscience (Cambridge, Mass.) · 2019Article
- On the nature and use of models in network neuroscience.Nature reviews. Neuroscience · 2018Review
- Correlated Gene Expression and Anatomical Communication Support Synchronized Brain Activity in the Mouse Functional Connectome.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- What We Know About the Brain Structure-Function Relationship.Behavioral sciences (Basel, Switzerland) · 2018Review
- Differentially categorized structural brain hubs are involved in different microstructural, functional, and cognitive characteristics and contribute to individual identification.Human brain mapping · 2018Article
- Development of large-scale functional networks from birth to adulthood: A guide to the neuroimaging literature.NeuroImage · 2017Review
- An active inference theory of allostasis and interoception in depression.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Article
- Virtual Cortical Resection Reveals Push-Pull Network Control Preceding Seizure Evolution.Neuron · 2016Article
- Multimodal analysis of cortical chemoarchitecture and macroscale fMRI resting-state functional connectivity.Human brain mapping · 2016Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mammalian cortex is a complex system of-at the microscale level-interconnected neurons and-at the macroscale level-interconnected areas, forming the infrastructure for local and global neural processing and information integration. While the effects of regional chemoarchitecture on local cortical activity are well known, the effect of local neurotransmitter receptor organization on the emergence of large scale region-to-region functional interactions remains poorly understood. Here, we examined reports of effective functional connectivity-as measured by the action of strychnine administration acting on the chemical balance of cortical areas-in relation to underlying regional variation in microscale neurotransmitter receptor density levels in the macaque cortex. Linking cortical variation in microscale receptor density levels to collated information on macroscale functional connectivity of the macaque cortex, we show macroscale patterns of effective corticocortical functional interactions-and in particular, the strength of connectivity of efferent macroscale pathways-to be related to the ratio of excitatory and inhibitory neurotransmitter receptor densities of cortical areas. Our findings provide evidence for the microscale chemoarchitecture of cortical areas to have a direct stimulating influence on the emergence of macroscale functional connectivity patterns in the mammalian brain. Hum Brain Mapp 37:1856-1865, 2016. © 2016 Wiley Periodicals, Inc.
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