Evidence map›Paper›PMID 26970191›Full record

ReviewProgress in molecular biology and translational science2016

Studies of RNA Sequence and Structure Using Nanopores.

Robert Y Henley, Spencer Carson, Meni Wanunu

Abstract readReview
In one paragraph

Review in Progress in molecular biology and translational science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Next-Generation Sequencing Technologies in Blood Group Typing.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2020
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Robert Y HenleyDepartment of Physics, Northeastern University, Boston, Massachusetts, USA.
Spencer CarsonDepartment of Physics, Northeastern University, Boston, Massachusetts, USA.
Meni WanunuDepartment of Physics, Northeastern University, Boston, Massachusetts, USA; Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts, USA. Electronic address: wanunu@neu.edu.

Funding

Picogram-level DNA sequencing using Nanopores and Zero-Mode WaveguidesR21HG006873 · NHGRI · NORTHEASTERN UNIVERSITY · PI KORLACH, JONAS, WANUNU, MENI · 2012 to 2014
$812k
NHGRI NIH HHS R21 HG006873
6 · The paper itself

Abstract

Nanopores are powerful single-molecule sensors with nanometer scale dimensions suitable for detection, quantification, and characterization of nucleic acids and proteins. Beyond sequencing applications, both biological and solid-state nanopores hold great promise as tools for studying the biophysical properties of RNA. In this review, we highlight selected landmark nanopore studies with regards to RNA sequencing, microRNA detection, RNA/ligand interactions, and RNA structural/conformational analysis.

Indexed as

NanoporesAnimalsBase SequenceHumansNucleic Acid ConformationPoint-of-Care SystemsRNASequence Analysis, RNARNAdrug screening assaymicroRNAnanoporeRNARNA conformationRNA–protein interactionRNA sequencingsingle-molecule

Identifiers

PMID26970191
PMCPMC5146985

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.