ReviewSeminars in oncology2016
Targeting obesity-related adipose tissue dysfunction to prevent cancer development and progression.
Review in Seminars in oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Persistent influence of past obesity on current adiponectin levels and mortality in patients with type 2 diabetes.The Korean journal of internal medicine · 2025Observational
- Benign Breast Disease, NSAIDs, and Postmenopausal Breast Cancer Risk in the CPS-II Cohort.Cancer prevention research (Philadelphia, Pa.) · 2023Article
- Investigating key cell types and molecules dynamics in PyMT mice model of breast cancer through a mathematical model.PLoS computational biology · 2022Article
- Expected and paradoxical effects of obesity on cancer treatment response.Reviews in endocrine & metabolic disorders · 2021Review
- Review
- Cancer Risk in Normal Weight Individuals with Metabolic Obesity: A Narrative Review.Cancer prevention research (Philadelphia, Pa.) · 2021Review
- Association of Bariatric Surgery Status with Reduced HER2+ Breast Cancers: a Retrospective Cohort Study.Obesity surgery · 2019Article
- Editorial: Diet, Inflammation and Colorectal Cancer.Frontiers in immunology · 2019Article
- Obesity, Type-2 Diabetes and Cancer: Mechanistic Insights.Critical reviews in oncogenesis · 2019Review
- Interaction with adipocytes induces lung adenocarcinoma A549 cell migration and tumor growth.Molecular medicine reports · 2018Article
- [Preliminary Study on the Effect of Adipocytes on the Biological Behaviors of Lung Adenocarcinoma A549 Cells in Tumor Microenvironment].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2018Article
- Diabetes Mellitus and Obesity as Risk Factors for Pancreatic Cancer.Journal of the Academy of Nutrition and Dietetics · 2018Review
- Epidemiology and biology of physical activity and cancer recurrence.Journal of molecular medicine (Berlin, Germany) · 2017Review
- Adipose Tissue Metabolism and Cancer Progression: Novel Insights from Gut Microbiota?Current pathobiology reports · 2017Review
- DHA increases adiponectin expression more effectively than EPA at relative low concentrations by regulating PPARγ and its phosphorylation at Ser273 in 3T3-L1 adipocytes.Nutrition & metabolism · 2017Article
- Role of Nampt and Visceral Adiposity in Esophagogastric Junction Adenocarcinoma.Journal of immunology research · 2017Article
- Obesity as a Risk Factor for Prostatic Enlargement: A Retrospective Cohort Study in Korea.International neurourology journal · 2016Article
- Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity.Oncotarget · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The incidence of obesity, a leading modifiable risk factor for common solid tumors, is increasing. Effective interventions are needed to minimize the public health implications of obesity. Although the mechanisms linking increased adiposity to malignancy are incompletely understood, growing evidence points to complex interactions among multiple systemic and tissue-specific pathways including inflamed white adipose tissue. The metabolic and inflammatory consequences of white adipose tissue dysfunction collectively provide a plausible explanation for the link between overweight/obesity and carcinogenesis. Gaining a better understanding of these underlying molecular pathways and developing risk assessment tools that identify at-risk populations will be critical in implementing effective and novel cancer prevention and management strategies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.