Trial reportHeart (British Cardiac Society)2016
Effects of a transitional palliative care model on patients with end-stage heart failure: a randomised controlled trial.
Trial report in Heart (British Cardiac Society), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers, 16 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
85 citing papers in PubMed, 16 syntheses or guidelines pooled it.
- Comparative effectiveness of transitional care interventions for hospital-to-home transition in heart failure: an updated systematic review and network meta-analysis.BMC cardiovascular disorders · 2026Pooled it
- How is Telehealth Used to Increase Access to Specialty Palliative Care? A Systematic Review.Journal of pain and symptom management · 2025Pooled it
- Pooled it
- Transitional Care Interventions From Hospital to Community to Reduce Health Care Use and Improve Patient Outcomes: A Systematic Review and Network Meta-Analysis.JAMA network open · 2023Pooled it
- Needs-based triggers for timely referral to palliative care for older adults severely affected by noncancer conditions: a systematic review and narrative synthesis.BMC palliative care · 2023Pooled it
- Factors associated with hospitalisations of patients with chronic heart failure approaching the end of life: A systematic review.Palliative medicine · 2022Pooled it
- Effectiveness and cost effectiveness of palliative care interventions in people with chronic heart failure and their caregivers: a systematic review.BMC palliative care · 2022Pooled it
- Effectiveness and Cost-Effectiveness of Case Management in Advanced Heart Failure Patients Attended in Primary Care: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- Comparison of Mortality and Hospital Readmissions Among Patients Receiving Virtual Ward Transitional Care vs Usual Postdischarge Care: A Systematic Review and Meta-analysis.JAMA network open · 2022Pooled it
- Pooled it
- The effectiveness and cost-effectiveness of hospital-based specialist palliative care for adults with advanced illness and their caregivers.The Cochrane database of systematic reviews · 2020Pooled it
- Comparing Specialty and Primary Palliative Care Interventions: Analysis of a Systematic Review.Journal of palliative medicine · 2020Pooled it
- Are the MORECare guidelines on reporting of attrition in palliative care research populations appropriate? A systematic review and meta-analysis of randomised controlled trials.BMC palliative care · 2020Pooled it
- Pooled it
- Palliative Care Interventions for Patients with Heart Failure: A Systematic Review and Meta-Analysis.Journal of palliative medicine · 2017Pooled it
- Pooled it
- Early palliative care in heart failure shows neutral effects across EF subtypes: an exploratory EPCHF secondary analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2026Trial
- The Effect of Mental Health Education on the Resilience and Psychosocial Adjustment in Patients with Heart Failure under the Care of Home Counseling and Nursing Services: A Randomized Controlled Trial.International journal of community based nursing and midwifery · 2026Trial
- Effects of a home-based palliative heart failure program on quality of life among the elderly: a clinical trial study.BMC palliative care · 2023Trial
- Perceptions of Need for Palliative Care in Recently Hospitalized Patients With Systolic Heart Failure.Journal of pain and symptom management · 2021Trial
25 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine the effects of home-based transitional palliative care for patients with end-stage heart failure (ESHF) after hospital discharge.
methodsThis was a randomised controlled trial conducted in three hospitals in Hong Kong. The recruited subjects were patients with ESHF who had been discharged home from hospitals and referred for palliative service, and who met the specified inclusion criteria. The interventions consisted of weekly home visits/telephone calls in the first 4 weeks then monthly follow-up, provided by a nurse case manager supported by a multidisciplinary team. The primary outcome measures were any readmission and count of readmissions within 4 and 12 weeks after index discharge, compared using χ(2) tests and Poisson regression, respectively. Secondarily, change in symptoms over time between control and intervention groups were evaluated using generalised estimating equation analyses of data collected using the Edmonton Symptom Assessment Scale (ESAS).
resultsThe intervention group (n=43) had a significantly lower readmission rate than the control group (n=41) at 12 weeks (intervention 33.6% vs control 61.0% χ(2)=6.8, p=0.009). The mean number (SE) of readmissions for the intervention and control groups was, respectively, 0.42 (0.10) and 1.10 (0.16) and the difference was significant (p=0.001). The relative risk (CI) for 12-week readmissions for the intervention group was 0.55 (0.35 to 0.88). There was no significant difference in readmissions between groups at 4 weeks. However, when compared with the control group, the intervention group experienced significantly higher clinical improvement in depression (45.9% vs 16.1%, p<0.05), dyspnoea (62.2% vs 29.0%, p<0.05) and total ESAS score (73.0% vs 41.4%, p<0.05) at 4 weeks. There were significant differences between groups in changes over time in quality of life (QOL) measured by McGill QOL (p<0.05) and chronic HF (p<0.01) questionnaires.
conclusionsThis study provides evidence of the effectiveness of a postdischarge transitional care palliative programme in reducing readmissions and improving symptom control among patients with ESHF. TRIAL REGISTRATION NUMBER: HKCTR-1562; Results.
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