ArticleBJOG : an international journal of obstetrics and gynaecology2016
Risk factors and newborn outcomes associated with maternal deaths in the UK from 2009 to 2013: a national case-control study.
Article in BJOG : an international journal of obstetrics and gynaecology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 5 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 5 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Interventions to reduce inequalities for pregnant women living with disadvantage in high-income countries: an umbrella review.BMC public health · 2025Pooled it
- Association between socioeconomic disadvantage and severe maternal morbidity and mortality in high-income countries: a systematic review.Journal of epidemiology and community health · 2025Pooled it
- Socioeconomic inequalities and adverse pregnancy outcomes in the UK and Republic of Ireland: a systematic review and meta-analysis.BMJ open · 2021Pooled it
- Pooled it
- Clinical practice guideline on pregnancy and renal disease.BMC nephrology · 2019Guideline
- Use of evidence from the UK Obstetric Surveillance System in policy and clinical practice: a descriptive study using citation tracking.NIHR open research · 2026Article
- Comparative efficacy and safety of Chinese patent medicines of iron deficiency anemia during pregnancy: A network meta-analysis.World journal of clinical cases · 2024Article
- Care and support during maternity for mothers affected by modern slavery: A scoping review.International journal of nursing studies advances · 2023Article
- Perinatal Psychoactive Substances Use: A Rising Perinatal Mental Health Concern.Journal of clinical medicine · 2023Review
- Observational
- Obstetric Medicine: the protocol for a prospective three-dimensional cohort study to assess maternity care for women with pre-existing conditions (ForMaT).Frontiers in medicine · 2023Article
- Protocol and statistical analysis plan for a randomized controlled trial of the effect of intravenous iron on anemia in Malawian pregnant women in their third trimester (REVAMP - TT).Gates open research · 2023Article
- Minoritised ethnic women's experiences of inequities and discrimination in maternity services in North-West England: a mixed-methods study.BMC pregnancy and childbirth · 2022Article
- Role of ethnicity in high-level obstetric clinical incidents: a review of cases from a large UK NHS maternity unit.BMJ open quality · 2022Review
- Observational
- A national population-based cohort study to investigate inequalities in maternal mortality in the United Kingdom, 2009-17.Paediatric and perinatal epidemiology · 2020Article
- Alcohol, smoking, and other substance use in the perinatal period.BMJ (Clinical research ed.) · 2020Article
- The change in haemoglobin concentration between the first and third trimesters of pregnancy: a population study.BMC pregnancy and childbirth · 2019Article
- How do women with social risk factors experience United Kingdom maternity care? A realist synthesis.Birth (Berkeley, Calif.) · 2019Article
- Severe Maternal Morbidity Among Stillbirth and Live Birth Deliveries in California.Obstetrics and gynecology · 2019Article
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3 authors at 1 institution in 1 country.
Funding
Abstract
objectivesTo identify the risk factors for and adverse newborn outcomes associated with maternal deaths from direct and indirect causes in the UK.
designUnmatched case-control analysis.
settingAll hospitals caring for pregnant women in the UK. POPULATION: Comprised 383 women who died (cases) from direct or indirect causes from 2009 to 2013 (Confidential Enquiry into Maternal Deaths in the UK) and 1516 women who did not have any life-threatening complications during pregnancy and childbirth (controls) obtained from UK Obstetric Surveillance System (UKOSS).
methodsMultivariable regression analyses were undertaken to examine potential risk factors, their incremental effects, and adverse newborn outcomes associated with maternal deaths. OUTCOMES: Odds ratios associated for risk factors for maternal death and newborn outcomes (stillbirth, admission to neonatal intensive care unit [NICU], early neonatal death) and incremental risk.
resultsSeven factors, of 13 examined, were independently associated with increased odds of maternal death: pre-existing medical comorbidities (adjusted odds ratio [aOR] 8.65; 95% CI 6.29-11.90), anaemia during pregnancy (aOR 3.58; 95% CI 1.14-11.21), previous pregnancy problems (aOR 1.85; 95% CI 1.33-2.57), inadequate use of antenatal care (aOR 46.85; 95% CI 19.61-111.94), substance misuse (aOR 12.21; 95% CI 2.33-63.98), unemployment (aOR 1.81; 95% CI 1.08-3.04) and maternal age (aOR 1.06; 95% CI 1.04-1.09). There was a four-fold increase in the odds of death per unit increase in the number of risk factors. Odds of stillbirth, admission to NICU and early neonatal death were higher among women who died.
conclusionThis study reiterates the need for optimal care for women with medical comorbidities and older age, and the importance of adequate antenatal care. It demonstrates the existence of socio-economic inequalities in maternal death in the UK. TWEETABLE ABSTRACT: Medical comorbidities and socio-economic inequalities are important risk factors for maternal death in the UK.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.